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Probiotics manipulate host cytokine response and induce antimicrobial peptides

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Abstract

Probiotics modulate production of both cytokine and antimicrobial peptides. This effect can be regarded as a part of complex interplay between them and the host.

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Abbreviations

HBD-2:

human β-defensin 2

IFN-γ:

interferon γ

IL:

interleukin

TGF-β:

transforming growth factor β

TLR:

Toll-like receptor

TNF-α:

tumor necrosis factor α

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This work was supported by grants 524/05/2248 and 523/05/0249 of theGrant Agency of the Czech Republic. Research Agreement no. 4 betweenInstitute of Microbiology andArdeypharm GmbH and theInstitutional Research Concept AV 0Z 5020 0510 of theInstitute of Microbiology. The work is dedicated to our long-time friend Dr. Jürgen Schulze.

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Trebichavský, I., Šplíchal, I. Probiotics manipulate host cytokine response and induce antimicrobial peptides. Folia Microbiol 51, 507–510 (2006). https://doi.org/10.1007/BF02931599

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