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Use of glutaraldehyde-treated erythrocytes as indicator cells for the identification of the Clq component on the macrophage membrane by a rossette assay

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Abstract

Glutaraldehyde-treated sheep red blood fells (EGA) form rosottes with maerophages of various origin. The binding of EGA to cell surface: is mediated by the membrane associated Clq as demonstrated by the inhibition of EGA rosette formation either after treatment of macrophages with anti-Clq serum or after treatment of EGA with Clq. The rosults clearly demonstrate that the EGA-binding receptor of macrophage is the Clq eomponent.

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References

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Authors and Affiliations

  1. Department of Immunology, Babes Institute, R-76201, Buchurest, Romania

    C. Pistol-Tånase, G. Zamfir, I. Moraru & V. Ghetie

Authors
  1. C. Pistol-Tånase
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  2. G. Zamfir
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  3. I. Moraru
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  4. V. Ghetie
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Additional information

We are greatful to Dr. Ilca Mårgineanu for her criticism and suggestions. The technical assistance of Miss Marinela Mårgineanu and Miss Cristina Catargiu is greatly appreciated.

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Pistol-Tånase, C., Zamfir, G., Moraru, I. et al. Use of glutaraldehyde-treated erythrocytes as indicator cells for the identification of the Clq component on the macrophage membrane by a rossette assay. Folia Microbiol 33, 140–143 (1988). https://doi.org/10.1007/BF02928081

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  • DOI: https://doi.org/10.1007/BF02928081

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