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Vliv chlortetracyklinu na činnost α-amylásy produkčního kmeneActinomyces aureofaciens

Хлортетрациклина влияние на деятельн остьα-амилаза от производства шт аммаactinomyces aureofaciens

The influence of chlortetracycline on the activity of α-amylase of the production strainactinomyces aureofaciens

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Резюме

Ингибирующее влиян ие на ehlortetracycline dextrination деятельнос ть поджелудочно- ами лаза была доказана. Это торможение явл яется обратимым и может быть снятаани онов органических кислот. В другой стороны, было установлено, что хлортетрацикл ина в высоких конце нтрациях(1.400 μg./ml.)только очень незначительно влияет на активност ьα-амилаза от произв одства штамма,Actinomyces aureofaciens. амилаза от производ ства штаммаα-амилаз а от плесениAspergillus oryzaeи из поджелудочной α амилаза в связи с хлортетрациклина. Ход деятельностиα-а милаза в течение ферментации из хло ртетрациклина по пр оизводству штаммActinomyces aureofaciens изучали

Summary

The inhibitory influence of ehlortetracycline on the dextrination activity of pancreatic α-amylase was demonstrated. This inhibition is reversible and can be removed by the anions of organic acids. On the other hand it was found that chlortetracycline in high concentrations (1.400 μg./ml.) only very slightly influences the activity of the α-amylase of the production strain,Actinomyces aureofaciens. This amylase, therefore, is entirely different from the α-amylase of the fungusAspergillus oryzae and from pancreatic α-amylase in relation to chlortetracycline. The course of the activity of α-amylase during fermentation of chlortetracycline by the production strainActinomyces aureofaciens was studied.

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Authors and Affiliations

  1. Mikrobiologické oddělení, Biologický ústav, Československá akademie věd, Praha

    Josef Rokos, Mikuláš Burger & Pavel Procházka

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  1. Josef Rokos
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  2. Mikuláš Burger
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  3. Pavel Procházka
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Rokos, J., Burger, M. & Procházka, P. Vliv chlortetracyklinu na činnost α-amylásy produkčního kmeneActinomyces aureofaciens . Folia Microbiol 2, 65–70 (1957). https://doi.org/10.1007/BF02927995

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  • DOI: https://doi.org/10.1007/BF02927995

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