Abstract
Mechanisms of regulation of biosynthesis of secondary metabolites in microorganisms under natural conditions differ from the regulation mechanisms resulting in an overproduction of these metabolites in industrial fermentations. The overproduction is attained by creating pathophysiological cultivation conditions and by using mutant strains which differ substantially from wild strains isolated from natural environment.
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Vaněk, Z., Blxtmauerová, M. Secondary metabolism and pathophysiology. Folia Microbiol 30, 393–395 (1985). https://doi.org/10.1007/BF02927595
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DOI: https://doi.org/10.1007/BF02927595