Skip to main content
SpringerLink
Log in

Control of the cell cycle ofCandida utilis by external conditions

  • Published:
Folia Microbiologica Aims and scope Submit manuscript

Abstract

A mathematical model of the cell cycle ofCandida utilis in a continuous culture was formulated with respect to dilution rate. It makes it possible to express the duration of morphological stages in minutes, separately for mother cells and daughter cells. These values were compared with equivalent parameters in batch cultures. Duration of the morphological stage with buds was much longer in batch cultures as compared with the same value determined for a continuous culture according to the mathematical model. When using cultivation apparatus with a higher aeration capacity the (S + G2) phase, i.e. the stage bearing the bud, was reduced also in the batch cultures and approached the values determined for the continuous culture by means of the mathematical model.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  • Madron F., Vevebka V., Vaněček V.: Statistical analysis of material balance of a chemical reactor.AIChE Journal 23, 482 (1977).

    Article  CAS  Google Scholar 

  • Rivin C.J., Fangman W.L.: Cell cycle phases expansion in nitrogen-limited cultures ofSaccharomycea cerevisiae.J.Cell Biol. 85, 96 (1980).

    Article  PubMed  CAS  Google Scholar 

  • Strbiblová E., Beban K.: Demonstration of yeast scars by fluorescent microscopy.Exp.Cell Bes. 30, 603 (1963).

    Article  Google Scholar 

  • Vairo L.R.: Methylene blue solution for staining dead yeast cells.Stain Technol. 36, 329 (1961).

    PubMed  CAS  Google Scholar 

  • Votbujba J., Vraná D.: Mathematical model of morphological differentiation in yeast population.1th Internat.Symp.Cont.Ciat., p. 31, (B. Sikyta, Z. Fenol, V. Poláček, Eds.). Prague 1978.

  • Vraná D., Lieblová J., Beran K.: Maturation and growth of daughter cells in dependence on the growth rate ofCandida utilis population.Proc. 3rd Internat.Spec.Symp. Yeasts, Invited Lectures, Part II, p. 286 (H. Suomalainen, C. Waller, Eds). Otanieni—Helsinki 1973.

  • Vraná D.: Daughter cells as an important factor in determining the physiological state of yeast population.Biotech.Bioeng. 18, 297 (1976).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Technical Microbiology, Institute of Microbiology, Czechoslovak Academy of Sciences, 142 20, Prague 4

    D. VranÁ & J. Votrutba

Authors
  1. D. VranÁ
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. J. Votrutba
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

A short version of the present communication was published at theConference on Yeasts, organized by the Biological Society of GDR, section of mycology, at the Ernst-Moritz-Arndt-Universität Greifswald, in May 1979.

Rights and permissions

Reprints and permissions

About this article

Cite this article

VranÁ, D., Votrutba, J. Control of the cell cycle ofCandida utilis by external conditions. Folia Microbiol 26, 382–387 (1981). https://doi.org/10.1007/BF02927331

Download citation

  • Received:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02927331

Keywords

Search

Navigation