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Diagnosis of pancreatic cancer

Serological markers

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International journal of pancreatology Aims and scope Submit manuscript

Summary

Many serological markers that are widely used for delecting pancreatic cancer are discussed. Some are good indicators, but others are not.

Among them, CA19-9 and SPan-1 radioimmunoassays have a higher sensitivity and specificity. However, these markers are neither tumor specific nor pancreatic cancer-specific. Accurate understanding of their measurement made it possible to diagnose pancreatic cancer, even when the cancer was small, and to monitor the patients after treatment.

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References

  1. Japan Pancreatic Society Annual Report of the Japanese Pancreatic Cancer Register, Japanese Pancreatic Cancer Register Committee, 1989.

  2. Satake K, Kanazawa G, Koh I, et al. Evaluation of serum pancreatic enzymes, carbohydrate antigen 19-9 and carcinoembryonic antigen in various pancreatic disease. Amer. J. Gasterenterol 1985; 80: 630–636.

    CAS  Google Scholar 

  3. Suzuki T, Naito A, Manabe T, et al. Clinics of the pancreatic cancer. Naika 1984; 53: 675–682.

    Google Scholar 

  4. Del Villano BC, Bremnen S, Block P, et al. Radioimmunometric assay for a monoclonal antibody defined tumor marker, CA19-9. Clin Chem. 1983; 29: 549–552.

    PubMed  Google Scholar 

  5. Tempero MA, Uchida E, Takasuki H, et al. Relationship of carbohydrate antigen 19-9 and Lewis antigens in pancreatic cancer. Cancer Res. 1987; 47: 5501–5503.

    PubMed  CAS  Google Scholar 

  6. Umeyama K. Clinical evalution of measurement of pancreatic cancer associated antigen SPan-1. J. Jpn. Pane. Soc. 1988; 3: 528–539.

    Google Scholar 

  7. Takemori Y, Sawabu N, Satomura Y, et al. The measurement of serum DUPAN-2 levels utilizing a EIA kit. Jpn. J. Cancer Chem. 1987; 14: 119–126.

    CAS  Google Scholar 

  8. chihara T, Nakao A, Sakamoto T, et al. CA50, CA19-9, DUPAN-2 in pancreatic cancer (II): Comparative studies of tissue distributions and serum level. Jpn. Pane. Soc. 1987; 2: 34–35.

    Google Scholar 

  9. Okura H, Tajiri H. Tumor markers in diagnosis of pancreatic cancer. Pharma. Medica. 1987; 5: 21–27.

    Google Scholar 

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Authors and Affiliations

  1. First Department of Surgery, Osaka City University, Medical School, 545, Asahi-Machi, Abeno-Ku, Osaka, Japan

    Katsusuke Satake

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  1. Katsusuke Satake
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Satake, K. Diagnosis of pancreatic cancer. Int J Pancreatol 9, 93–98 (1991). https://doi.org/10.1007/BF02925584

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  • DOI: https://doi.org/10.1007/BF02925584

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