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Ductal adenocarcinoma of the pancreas

Histopathological features and prognosis

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International journal of pancreatology Aims and scope Submit manuscript

Summary

Between 1972 and 1987, curative surgical resection (RO) was performed in 81 patients with ductal adenocarcinoma of the pancreas. In this study, slides from surgical specimens were reviewed, and histopathological features of the carcinomas were retrospectively reevaluated. Tumor stage was the most important prognostic factor: In UICC stages I, II, and III, the median survival times were 13, 16, and 8 mo, respectively. Lymph node involvement and direct extension of the tumor into adjacent peripancreatic tissue, as well as invasion into peripancreatic organs were found to significantly influence survival. Tumor infiltration of the lymphatic vessels was present in 74% of the resected carcinomas and significantly correlated with survival time. There was no relationship between survival and tumor size; furthermore, histological grade of differentiation, age, and sex had no influence on prognosis.

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Authors and Affiliations

  1. Department of Pathology, Medizinische Hochschule Hannover, Hannover, Germany

    Andrea Tannapfel

  2. Department of Surgical and Urological Pathology, Friedrich-Alexander University, W-8520, Erlangen, Germany

    Christian Wittekind

  3. Department of Surgery, Evangelisches Krankenhaus e. V., Göttingen—Weende, Germany

    Günther Hünefeld

Authors
  1. Andrea Tannapfel
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  2. Christian Wittekind
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  3. Günther Hünefeld
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Tannapfel, A., Wittekind, C. & Hünefeld, G. Ductal adenocarcinoma of the pancreas. Int J Pancreatol 12, 145–152 (1992). https://doi.org/10.1007/BF02924638

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  • DOI: https://doi.org/10.1007/BF02924638

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