Skip to main content
SpringerLink
Log in

Growth features of T-cell receptor gamma/delta-positive cell clones

  • Intraepithelial Lymphocytes/γδ T Cells
  • Published:
Immunologic Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Brenner MB, McLean J, Dialynas DBP, Strominger JL, Smith JA, Owen FL, Seidman JP, Ip S, Rosen F, Krangel MS: Identification of a putative second T cell receptor. Nature 1986;322:145–149.

    Article  PubMed  CAS  Google Scholar 

  2. Moingeon P, Ythier A, Goubin G, Faure F, Novill A, Delmon L, Reinaud M, Forestier F, Dafos F, Bohuon C, Hercend T: A unique T-cell receptor complex expressed on human fetal lymphocytes displaying natural killer-like activity. Nature 1986;323:638–640.

    Article  PubMed  CAS  Google Scholar 

  3. Bottino C, Tambussi G, Ferrini S, Ciccone E, Varese P, Mingari MC, Moretta L, Moretta A: Two subsets of human T lymphocytes expressing gamma/delta antigen receptor are identifiable by monoclonal antibodies directed to two distinct molecular forms of the receptor. J Exp Med 1988; 168:481–505.

    Article  Google Scholar 

  4. Miossec C, Faure F, Ferradini L, Roman-Roman S, Jitsukawa S, Ferrini S, Moretta A, Triebel F, Hercend T: Further analysis of the T cell receptor gamma/delta+ peripheral lymphocytes subset. J Exp Med 1990;171:1171–1188.

    Article  PubMed  CAS  Google Scholar 

  5. Ciccone E, Ferrini S, Bottino C, Viale O, Prigione I, Pantaleo G, Tambussi G, Moretta A, Moretta L: A monoclonal antibody specific for a common determinant of the human T cell receptor gamma/delta directly activates CD3+WT31− lymphocytes to express their functional program(s). J Exp Med 1988;168:1–11.

    Article  PubMed  CAS  Google Scholar 

  6. Triebel F, Faure F, Mami-Chonaib F, Jitsukawa S, Griscelli A, Geneve C, Roman-Roman S, Hercend T: A novel human Vdelta gene expressed predominantly in the TigammaA fraction of gamma/delta peripheral lymphocytes. Eur J Immunol 1988;18:2021–2027.

    Article  PubMed  CAS  Google Scholar 

  7. Mami-Chonaib F, Jitsukawa S, Faure F, Vasina B, Geneve C, Hercend T, Triebel F: cDNA cloning of functional gamma and delta receptor chains in peripheral blood lymphocytes. Eur J Immunol 1989;19:1545–1549.

    Article  Google Scholar 

  8. Goodman T, Le Francois L: Expression of the gamma/delta T-cell receptor on intestinal CD8+ intraepithelial lymphocytes. Nature 1988;333:855–858.

    Article  PubMed  CAS  Google Scholar 

  9. Janeway CA, Jones B, Hayday A: Specificity and function of T cells bearing gamma/delta receptors. Immunol Today 1988;9:73–76.

    Article  PubMed  Google Scholar 

  10. Groh V, Porcelli S, Fabbi M, Lanier LL, Picker LJ, Anderson T, Warnke RA, Bhan AK, Strominger JL, Brenner MB: Human lymphocytes bearing T cell receptor gamma/delta are phenotypically diverse and evenly distributed throughout the lymphoid system. J Exp Med 1989;169:1277–1294.

    Article  PubMed  CAS  Google Scholar 

  11. Bucy RP, Chen CH, Cihak J, Losch K, Cooper MD: Avian T cells expressing gamma/delta receptors localize in the splenic sinusoids and the intestinal epithelium. J Immunol 1988;141:2200–2205.

    PubMed  CAS  Google Scholar 

  12. Falini B, Flenghi L, Pileri S, Pelicci P, Fagioli M, Martelli MF, Moretta L, Ciccone E: Distribution of T cells bearing different forms of the T cell receptor gamma/delta in normal and pathological human tissues. J Immunol 1989;143:2480–2488.

    PubMed  CAS  Google Scholar 

  13. Grossi CE, Ciccone E, Migone N, Bottino C, Zarcone D, Mingari MC, Ferrini S, Tambussi G, Viale O, Casorati G, Millo R, Moretta L, Moretta A: Human T cells expressing the gamma/delta T cell receptor (TcR-1). Cgamma1 and Cgamma2 encoded forms of the receptor correlate with distinctive morphology, cytoskeletal organization and growth characteristics. Proc Natl Acad Sci USA 1989;86:1619–1623.

    Article  PubMed  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Laboratorio di Ultrastructure, Istituto Superiore di Sanità, Viale Regina Elena 299, I-00161, Roma, Italy

    G. Arancia, W. Malorni, F. Iosi, D. Zarcone, G. Cerruti, A. Moretta & C. E. Grossi

  2. Istitute di Anatomia e Istologia, Università di Genova, Genova, Italia

    G. Arancia, W. Malorni, F. Iosi, D. Zarcone, G. Cerruti, A. Moretta & C. E. Grossi

  3. Istitute Nazionale per la Ricerca sul Cancro, Genova, Italia

    G. Arancia, W. Malorni, F. Iosi, D. Zarcone, G. Cerruti, A. Moretta & C. E. Grossi

Authors
  1. G. Arancia
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. W. Malorni
    View author publications

    You can also search for this author in PubMed Google Scholar

  3. F. Iosi
    View author publications

    You can also search for this author in PubMed Google Scholar

  4. D. Zarcone
    View author publications

    You can also search for this author in PubMed Google Scholar

  5. G. Cerruti
    View author publications

    You can also search for this author in PubMed Google Scholar

  6. A. Moretta
    View author publications

    You can also search for this author in PubMed Google Scholar

  7. C. E. Grossi
    View author publications

    You can also search for this author in PubMed Google Scholar

Additional information

Supported by grants from AIRC (Associazione Italiana per la Ricerca sul Canero) and CNR (PF Biotecnologie).

Rights and permissions

Reprints and permissions

About this article

Cite this article

Arancia, G., Malorni, W., Iosi, F. et al. Growth features of T-cell receptor gamma/delta-positive cell clones. Immunol Res 10, 331–333 (1991). https://doi.org/10.1007/BF02919717

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02919717

Keywords

Search

Navigation