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Antigen presenting cells

  • Cellular Immunology
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References

  1. Meuer SC, Schlossman SF, Reinherz EL: Clonal analysis of human T lymphocytes: T4-positive and T8-positive effector T cells recognize products of different major histocompatibility complex regions. Proc Natl Acad Sci USA 1982;79: 4395.

    PubMed  CAS  Google Scholar 

  2. Braciale TJ, Morrison LA, Sweetser MT, et al: Antigen presentation pathways to class I and class II MHC-restricted T lymphocytes. Immunol Rev 1987;98:95–114.

    PubMed  CAS  Google Scholar 

  3. Swain SL: T cell subsets and the recognition of MHC class. Immunol Rev 1983;74:129–142.

    PubMed  CAS  Google Scholar 

  4. Bjercke S: Effect of interferon gamma on expression of HLA-class II molecules on blood-derived dendritic cells. Acta Pathol Microbiol Immunol Scand 1987;95:137–140.

    CAS  Google Scholar 

  5. Nawroth PP, Bank I, Handley D, et al: Tumor necrosis factor/cachectin interacts with endothelial cell receptors to induce release of interleukin 1. J Exp Med 1986;163:1363–1375.

    PubMed  CAS  Google Scholar 

  6. Ghiara P, Boraschi D, Nencioni L, et al: Enhancement of in vivo immune response by tumor necrosis factor. J Immunol 1987;139:3676–3679.

    PubMed  CAS  Google Scholar 

  7. Morrissey PJ, Bressler L, Park LS, et al: Granulocyte-macrophage colony-stimulating factor augments the primary antibody response by enhancing the function of antigen-presenting cells. J Immunol 1987;139:1113–1119.

    PubMed  CAS  Google Scholar 

  8. Koide S, Inaba K, Steinman RM: Interleukin 1 enhance T-dependent immune responses by amplifying the function of dendritic cells. J Exp Med 1987;165:515–530.

    PubMed  CAS  Google Scholar 

  9. Inaba K, Witmer-Pack MD, Inaba M, et al: The function of Ia+ dendritic cells and Ia− dendritic cell precursors in thymocyte mitogenesis to lectin and lectin plus interleukin-1. J. Exp Med 1988: 167:149–162.

    PubMed  CAS  Google Scholar 

  10. Zlotnik A, Fischer M, Roehm N, et al: Evidence for effects of interleukin 4 (B cell stimulatory factor 1) on macrophages: Enhancement of antigen presenting ability of bone marrow-derived macrophages. J Immunol 1987;138:4275–4279.

    PubMed  CAS  Google Scholar 

  11. Monick M, Glazier J, Hunninghake G: Human alveolar macrophages suppress interleukin-1 (IL-1) activity via the secretion of prostaglandin E2. Am Rev Respir Dis 1987;135:72–77.

    PubMed  CAS  Google Scholar 

  12. Rich EA, Tweardy DJ, Fujiwara H, et al: Spectrum of immunoregulatory functions and properties of human alveolar macrophages. Am Rev Respir Dis 1987;136:258–265.

    PubMed  CAS  Google Scholar 

  13. Shah PD: Dendritic cells but not macrophages are targets for immune regulation by natural killer cells. Cell Immunol 1987;104:440–445.

    PubMed  CAS  Google Scholar 

  14. Unanue ER, Beller DI, Lu CY, et al: Antigen presentation: Its regulation and mechanism. J Immunol 1984;132:1–5.

    PubMed  CAS  Google Scholar 

  15. Takacs L, Berzofsky JA, York-Jolley J, et al: IL-1 induction by murine T cell clones: Detection of an IL-1 inducing factor. J Immunol 1987;138:2124–2131.

    PubMed  CAS  Google Scholar 

  16. Unanue ER, Weaver CT, Fuhlbrigge RC, et al: Membrane IL-1: a key protein in antigen presentation. Ann Inst Pasteur Immunol 1987;138:489–492.

    Article  PubMed  CAS  Google Scholar 

  17. Unanue ER, Allen PM: The basis for the immunoregulatory role of macrophages and other accessory cells. Science 1987;236:551–557.

    PubMed  CAS  Google Scholar 

  18. Chesnut RW, Grey HM: Antigen presenting cells and mechanisms of antigen presentation. CRC Crit Rev Immunol 1984;5:263–316.

    Google Scholar 

  19. Katz SI, Cooper KD, Iljima M, et al The role of Langerhans cells in antigen presentation. J Invest Dermatol 1985;85(suppl): 96s-98s.

    PubMed  CAS  Google Scholar 

  20. Luger TA, Stadtler BM, Katz SI, et al: Epidermal cell (keratinocyte) derived thymocyte-activating factor (ETAF). J Immunol 1981;127:1493–1498.

    PubMed  CAS  Google Scholar 

  21. Kupper TS, Ballard DW, Chua AO, et al: Human keratinocytes contain mRNA indistinguishable from monocyte interleukin-1-alpha and-beta mRNA. Keratinocyte-epidermal cell-derived thymocyte-activating factor is identical to interleukin-1. J Exp Med 1986;164:2095–2010.

    PubMed  CAS  Google Scholar 

  22. Hamilos DL: Immunocompetent dendritic cells; in Cruse JM, Lewis RE Jr (eds): The Year in Immunology 1986–1987. Basel, Karger, 1988, vol 3, pp 89–118.

    Google Scholar 

  23. Guidos C, Wong M, Lee K: A comparison of stimulatory activities of lymphoid dendritic cells and macrophages in T lymphoproliferative responses to various antigens. J Immunol 1984;133:1179–1184.

    PubMed  CAS  Google Scholar 

  24. Mittal A, Nath I: Human T cell proliferative responses to particulate microbial antigens are supported by populations enriched in dendritic cells. Clin Exp Immunol 1987;69:611–617.

    PubMed  CAS  Google Scholar 

  25. Kawai J, Inaba K, Komatsubara S, et al: Role of macrophages as modulators but not as autonomous accessory cells in the proliferative response of immune T cells to soluble antigen. Cell Immunol 1987;109:1–11.

    PubMed  Google Scholar 

  26. Kaye PM, Chain BM, Feldmann M: Nonphagocytic dendritic cells are effective accessory cells for anti-mycobacterial responses in vitro. J Immunol 1985;134:1930–1934.

    PubMed  CAS  Google Scholar 

  27. Moss B, Flexner C: Vaccinia virus expression vectors. Annu Rev Immunol 1987;5:305–324.

    PubMed  CAS  Google Scholar 

  28. Ciavarra RP: Activated but not resting B cells act as potent antigen presenting cells for vesicular stomatitis virus Cytotoxic T cells; in Schook LB, Tew JG (eds). Antigen Presenting Cells: Diversity, Differentiation and Regulation. New York, Liss, 1988.

    Google Scholar 

  29. Fauci AS: The human immunodeficiency virus: Infectivity and mechanisms of pathogenesis. Science 1988;239:617–622.

    PubMed  CAS  Google Scholar 

  30. Chantal Petit AJ, Tersmette M, Terpstra FG, et al: Decreased accessory cell function by human monocytic cells after infection with HIV. J Immunol 1988;140:1485–1489.

    Google Scholar 

  31. Pontesilli O, Carotenuto P, Levin MJ, et al: Processing and presentation of cell-associated varicella zoster virus antigens by human monocytes. Clin Exp Immunol 1987;70; 127–135.

    PubMed  CAS  Google Scholar 

  32. Lechler RI, Batchelor JR: Restoration of immunogenicity to passenger cell depleted kidney allografts by the addition of donor strain dendritic cells. J Exp Med 1982;155:31.

    PubMed  CAS  Google Scholar 

  33. Chain BM, Kaye PM, Feldman M: The cellular pathway of antigen presentation: Biochemical and functional analysis of antigen prosentation: Biochemical and functional analysis of antigen processing in dendritic cells and macrophages. Immunology 1986; 58:271–276.

    PubMed  CAS  Google Scholar 

  34. Sunshine GH, Mitchell TJ: Antigen presentation by splenic dendritic cells. J Invest Dermatol 1985; 85:110s-114s.

    PubMed  CAS  Google Scholar 

  35. Inaba K, Steinman RM: Accessory cell-T lymphocyte interaction: antigen-dependent and-independent clustering. J Exp Med 1986;163:247.

    PubMed  CAS  Google Scholar 

  36. Davignon D, Martz E, Reynolds T, et al: Monoclonal antibody to a novel lymphocyte function-associated antigen (LFA-1): Mechanism of blocking of T lymphocyte mediated killing and effects on other T and B lymphocyte functions. J Immunol 1981;127:590.

    PubMed  CAS  Google Scholar 

  37. Inaba K, Steinman RM: Monoclonal antibodies to LFA-1 and to CD4 inhibit the mixed leukocyte reaction after the antigen dependent clustering of dendritic cells and T lymphocytes. J Exp Med 1987;165:1403–1417.

    PubMed  CAS  Google Scholar 

  38. Inaba K, Young JW, Steinman RM: Direct activation of CD8 positive cytotoxic T lymphocytes by dendritic cells. J Exp Med 1987;166:182–194.

    PubMed  CAS  Google Scholar 

  39. Lafferty KJ: Immunogenicity of foreign tissues. Transplantation 1980;29:179.

    Article  PubMed  CAS  Google Scholar 

  40. Faustman D, Lacy PE, Davie JM: Transplantation without immunosuppression. Diabetes 1982; 31 (suppl 4): 11–14.

    PubMed  Google Scholar 

  41. Faustman DL; Steinman RM, Gebel HM, et al: Prevention of rejection of murine islet allografts by pretreatment with antidendritic cell antibody. Proc Natl Acad Sci USA 1984;81:3864–3868.

    PubMed  CAS  Google Scholar 

  42. Sontheimer RD: The mixed epidermal cell-lymphocyte reaction. II. Epidermal Langerhans cells are responsible for the enhanced allogenic lymphocyte-stimulating capacity of normal human epidermal cell suspensions. J Invest Dermatol 1985;85:21s-26s.

    PubMed  CAS  Google Scholar 

  43. Chen HD, Raab S, Silvers WK: Influence of major histocompatibility complex compatible and incompatible Langerhans cells on the survival of HY-incompatible skin grafts in rats. Transplantation 1985;40:194–197.

    PubMed  CAS  Google Scholar 

  44. Inaba K, Steinman RM: Resting and sensitized T lymphocytes exhibit distinct stimulatory (antigen presenting cell) requirements for growth and lymphokine release. J Exp Med 1984;160:1717–1735.

    PubMed  CAS  Google Scholar 

  45. Steinman RM; Gutchinov B, Witmer MD, et al: Dendritic cells are the principle stimulators of the primary mixed leukocyte reaction in mice. J Exp Med 1983;157:613–627.

    PubMed  CAS  Google Scholar 

  46. Inaba K, Witmer MD, Stienman RM: Clustering of dendritic cells, helper T lymphocytes, and histocompatible B cells during primary antibody responses in vitro. J Exp Med 1984;160:858–876.

    PubMed  CAS  Google Scholar 

  47. Krieger JI, Grammer SF, Grey HM, et al: Antigen presentation by splenic B cells: Resting B cells are ineffective whereas activated B cells are effective accessory cells for T cells responses. J Immunol 1985;135:2937–2945.

    PubMed  CAS  Google Scholar 

  48. Krieger JI, Chesnut RW, Grey HM: Capacity of B cells to function as stimulatory of a primary mixed leukocyte reaction. J Immunol 1986;137:3117–3123.

    PubMed  CAS  Google Scholar 

  49. Webb SR, Li JH, Wilson DB, et al: Capacity of small B cell-enriched populations to stimulate mixed lymphocyte reactions: marked differences between irradiated vs. mitomycin C-treated stimulators. Eur J Immunol 1985;15:92.

    PubMed  CAS  Google Scholar 

  50. Ron Y, Sprent J: T cell priming in vivo: A major role for B cells in presenting antigen to T cells in lymph nodes. J Immunol 1987;138:2848–2856.

    PubMed  CAS  Google Scholar 

  51. Ron Y, Sprent J: B cells as antigen presenting cells in vivo; in Schook LB, Tew JG (eds): Antigen Presenting Cells: Diversity, Differentiation and Regulation. New York: Liss. 1988, pp 321–329.

    Google Scholar 

  52. Janeway CA, Ron J, Katz ME: The B cell is the initiating antigen presenting cell in peripheral lymph nodes. J Immunol 1987; 138: 1051–1055.

    PubMed  Google Scholar 

  53. Casten LA, Pierce SK: Receptor-mediated B cell antigen processing. Increased antigenicity of a globular protein covalently coupled to antibodies specific for B cell surface structures. J Immunol 1988; 140: 404–410.

    PubMed  CAS  Google Scholar 

  54. Ochi A, Worton KS, Woods G, et al: A novel strategy for immunotherapy using antibody-coupled carriers to focus cytotoxic T helper cells. Eur J Immunol 1987; 17: 1645–1648.

    PubMed  CAS  Google Scholar 

  55. Swain SL, Dutton RW: Consequences of direct interaction of helper T cells with B cells presenting antigen. Immunol Rev 1987; 99: 263–280.

    PubMed  CAS  Google Scholar 

  56. Czitrom AA; Sunshine GH, Reme E, et al: Stimulator cell requirements for allospecific T cell subsets: Specialized accessory cells are required to activate helper but not cytolytic T lymphocyte precursors. J Immunol 1983; 130: 546–550.

    PubMed  CAS  Google Scholar 

  57. Czitrom AA, Katz DR, Sunshine GH: Alloreactive cytotoxic T lymphocyte responses to H-2 products on purified accessory cells. Immunology 1982; 45: 553–560.

    PubMed  CAS  Google Scholar 

  58. Czitrom AA, Edwards S, Katz DR, et al: Characterization of stimulator cells for alloreactive cytotoxic T lymphocyte responses in vivo. Cell Immunol 1985; 90: 503–513.

    PubMed  CAS  Google Scholar 

  59. Kappler JW, Skidmore B, White J, et al: Antigen-inducible H-2-restricted interleukin-2-producing T cell hybridomas. J Exp Med 1981; 153: 1198–1214.

    PubMed  CAS  Google Scholar 

  60. Hamilos DL: The T cell receptor for antigen. A critique of recent experimental literature. Surv Synth Pathol Res 1984; 3: 292–310.

    PubMed  CAS  Google Scholar 

  61. Heber-Katz E, Hansburg D, Schwartz RH: The Ia molecule of the antigen-presenting cell plays a critical role in immune response gene regulation of T cell activation. J Mol Cell Biol 1983; 1: 3–14.

    CAS  Google Scholar 

  62. Rosenthal AS: Determinant selection and macrophage function in genetics control of the immune response. Immunol Rev 1978; 40: 136.

    PubMed  CAS  Google Scholar 

  63. Sercarz EE, Metzger DW: Epitope-specific and idiotype-specific cellular interactions in a model protein antigen system. Springer Semin Immunopathol 1980; 3: 145–170.

    PubMed  CAS  Google Scholar 

  64. Buus S, Sette A, Grey HM: The interaction between protein derived immunogenic peptides and IA. Immunol Rev 1987; 98: 115–141.

    PubMed  CAS  Google Scholar 

  65. Babbit BP, Allen PM, Matsueda G, et al: Binding of immunogenic peptides to Ia histocompatibility molecules. Nature 1985; 317: 359.

    Google Scholar 

  66. Buus S, Sette A, Colon SM, et al: The relation between major histocompatibility complex (MHC) restriction and the capacity of Ia to bind immunogenic peptides. Science 1987; 235: 1353.

    PubMed  CAS  Google Scholar 

  67. Lakey EK, Casten LA, Anderson MS, et al: T cell activation by processed antigen is equally blocked by IE and IA restricted immunodominant peptides. Eur J Immunol 1987; 17: 1605–1609.

    PubMed  CAS  Google Scholar 

  68. Mellins E, Woelfel M, Pious D: Importance of HLA-DQ and-DP restriction elements in T cell responses to soluble antigen. Mutational analysis. Hum Immunol 1987; 18: 211–223.

    PubMed  CAS  Google Scholar 

  69. Nunez G, Ball EJ, Stastny P: Antigen presentation by adherent cells from human peripheral blood. Correlation between T cell activation and expression of HLA-DQ and-DR antigens. Hum Immunol 1987; 19: 29–39.

    PubMed  CAS  Google Scholar 

  70. Unanue ER, Allen PM: The basis for the immunoregulatory role of macrophages and other accessory cells. Science 1987; 236: 551–557.

    PubMed  CAS  Google Scholar 

  71. Sette A, Buus S, Colon S, et al: Structural characteristics of an antigen required for its interaction with Ia and recognition by T cells. Nature 1987; 328: 395–399.

    PubMed  CAS  Google Scholar 

  72. Bjorkman PJ, Saper MA, Samraoui B, et al: Structure of the human class I histocompatibility antigen, HLA-AS2. Nature 1987; 329: 506–512.

    PubMed  CAS  Google Scholar 

  73. Bjorkman PJ, Saper MA, Samraoui B, et al: The foreign antigen binding site and T cell recognition regions of class I histocompatibility antigens. Nature 1987; 329: 512–518.

    PubMed  CAS  Google Scholar 

  74. Lakey EK, Margoliash E, Pierce SK: Identification of a peptide binding protein that plays a role in antigen presentation. Proc Natl Acad Sci USA 1987; 84: 1659–1663.

    PubMed  CAS  Google Scholar 

  75. Betancourt SB, Solvay MJ, Irani DN, et al: Heterogeneity in cellular antigen retention structures. J Immunol 1987; 139: 3725–3729.

    PubMed  CAS  Google Scholar 

  76. Falo LD, Haber SI, Herman S, et al: Characterization of antigen association with accessory cells: Specific removal of processed antigen from the cell surface by phospholipases. Proc Natl Acad Sci USA 1987; 84: 522–526.

    PubMed  CAS  Google Scholar 

  77. Kurt-Jones EA, Hamburg S, Ohara J, et al: Heterogeneity of helper/inducer T lymphocytes. I. Lymphokine production and lymphokine responsiveness. J Exp Med 1987; 166: 1774–1787.

    PubMed  CAS  Google Scholar 

  78. Chatila TA, Schwartz DH, Miller R, et al: Re-quirement for mitogen, T cell-accessory cell contact, and interleukin-1 in the induction of resting T cell proliferation. Clin Immunol Immunopathol 1987; 44: 235–247.

    PubMed  CAS  Google Scholar 

  79. Geppert TD, Lipsky PE: Antigen presentation by interferon-gamma-treated endothelial cells and fibroblasts: Differential ability to function as antigen-presenting cells despite comparable Ia expression. J Immunol 1985; 135: 3750–3762.

    PubMed  CAS  Google Scholar 

  80. Hurme M: Membrane-associated interleukin-1 is required for the activation of T cells in the anti-CD3 antibody-induced T cell response. J Immunol 1987; 139: 1168–1172.

    PubMed  CAS  Google Scholar 

  81. Nagelkerken L, Breda-Vriesman PJC van: Membrane-associated IL-1-like activity on rat dendritic cells. J Immunol 1986; 136: 2164–2170.

    PubMed  CAS  Google Scholar 

  82. Kurt-Jones EA, Beller DI, Mizel SB, et al: Identification of a membrane-associated interleukin-1 in macrophages. Proc Natl Acad Sci USA 1985; 82: 1204–1212.

    PubMed  CAS  Google Scholar 

  83. Saunder DN, Dinarello CA, Morhenn VB: Langerhans cells production of interleukin-1. J Invest Dermatol 1984; 82: 605–607.

    Google Scholar 

  84. Waalen J, Duff GW, Forre O, et al: Interleukin-1 activity produced by human rheumatoid and normal dendritic cells. Scand J Immunol 1986; 23: 365–371.

    PubMed  CAS  Google Scholar 

  85. Oppenheim JJ, Kovacs EJ, Matsushima K, et al: There is more than one interleukin 1. Immunol Today 1986; 7: 45–56.

    CAS  Google Scholar 

  86. Hopp TP, Dower SK, March CJ: The molecular forms of interleukin-1. Immunol Res 1986; 5: 271–280.

    Article  PubMed  CAS  Google Scholar 

  87. Lomedico PT, Kilian PL, Gubler U, et al: Molecular biology of interleukin-1. Cold Spring Harbor Symp Quant Biol 1986; 51: 631–639.

    PubMed  CAS  Google Scholar 

  88. Goldminz D, Kupper TS, McGuire J: Keratinocyte membrane-associated epidermal cell-derived thymocyte activating factor (ETAF). J Invest Dermatol 1987; 88: 97–100.

    PubMed  CAS  Google Scholar 

  89. Springer TA, Davignon D, Ho MK, et al: LFA-1 and Lyt2,3 molecules associated with T lymphocyte-mediated killing; and Mac-1, and LFA-1 homologue, associated with complement receptor function. Immunol Rev 1982; 68: 171–195.

    PubMed  CAS  Google Scholar 

  90. Krensky AM, Sanchez-Madrid F, Robbins E, et al: The functional significance, distribution and structure of LFA-1, LFA-2, and LFA-3: cell surface antigens associated with CTL-target cell interactions. J Immunol 1983; 131: 611–616.

    PubMed  CAS  Google Scholar 

  91. Krensky AM, Robbins E, Springer TS, et al: LFA-1, LFA-2, and LFA-3 antigen are involved in CTL target conjugation. J Immunol 1984; 132: 2180–2182.

    PubMed  CAS  Google Scholar 

  92. Dongworth DW, Gotch FM, Hildreth JEK, et al: Effects of monoclonal antibodies to the alpha and beta chains of the human lymphocyte function-associated (H-LFA-1) antigen on T lymphocyte functions. Eur J Immunol 1985; 15: 888–892.

    PubMed  CAS  Google Scholar 

  93. Martz E, Gromkowski SH: Lymphocyte function associated antigens: Regulation of lymphocyte adhesion in vitro and immunity in vivo. Adv Exp Med Biol 1985; 184: 291–310.

    PubMed  CAS  Google Scholar 

  94. Hemler ME: Adhesive protein receptors on hematopoietic cells. Immunol Today 1988; 9: 109–113.

    PubMed  CAS  Google Scholar 

  95. Plunkett ML, Sanders ME, Selvaraj P, et al: Rosetting of activated human T lymphocytes with autologous erythrocytes. Definition of the receptor and ligand molecules as CD2 and lymphocyte function-associated antigen 3 (LFA-3). J Exp Med 1987; 165: 664–676.

    PubMed  CAS  Google Scholar 

  96. Dustin M, Sanders M, Shaw S, et al: Purification and CD2 binding function of LFA-3 (abstract). Fed Proc 1987; 46: 1498.

    Google Scholar 

  97. Vollger LW, Tuck DT, Springer TA, et al: Thymocyte binding to human thymic epithelial cells is inhibited by monoclonal antibodies to CD2 and LFA-3 antigens. J Immunol 1987; 138: 358–363.

    PubMed  CAS  Google Scholar 

  98. Rothlein R, Dustin ML, Marlin SD, et al: A human intercellular adhesion molecule (ICAM-1) distinct from LFA-1. J Immunol 1986; 137: 1270–1274.

    PubMed  CAS  Google Scholar 

  99. Dougherty GJ, Hogg N: The role of monocyte lymphocyte function-associated antigen-1 (LFA-1) in accessory cell function. Eur J Immunol 1987; 17: 943–947.

    PubMed  CAS  Google Scholar 

  100. Krieger JI, Jenis DM, Chesnut RW, et al: Studies on the capacity of intact cells and purified Ia of different B cell sources to function in antigen presentation to T cells. J Immunol 1988; 140: 388–394.

    PubMed  CAS  Google Scholar 

  101. Kradin RL, McCarthy KM, Daily CI, et al: The poor accessory cell function in the rat may reflect their inability to form clusters with T cells. Clin Immunol Immunopathol 1987; 44: 348–363.

    PubMed  CAS  Google Scholar 

  102. Kupfer A, Swain SL, Janeway CA, et al: The specific direct interaction of helper T cells and antigen-presenting B cell. Proc Natl Acad Sci 1986; 83:6080–6083.

    PubMed  CAS  Google Scholar 

  103. Marrack P, Endres R, Shimonkevitz R, et al: The major histocompatibility complex-restricted antigen receptor on T cells. II. Role of the L3T4 product. J Exp Med 1983; 158: 1077.

    PubMed  CAS  Google Scholar 

  104. Dialynas DP, Quan ZS, Wall Ka, et al: Characterization of the murine T cell surface molecule, designated L3T4, identified by monoclonal antibody GK-1.5: Similarity of L3T4 to the human leu3/T4 molecule. J Immunol 1983; 131: 2445.

    PubMed  CAS  Google Scholar 

  105. Swain SI, Dialynas DP, Fitch FW, et al: Monoclonal antibody to L3T4 blocks the function of T cells specific for class 2 major histocompatibility complex antigens. J Immunol 1984; 132: 1118–1123.

    PubMed  CAS  Google Scholar 

  106. Hamilos DL, Mascali JJ, Chesnut RW, Young RM, Ishioka G, Grey HM: The role of dendritic cells as stimulators of Mls-specific T cell responses in the mouse. I. Differential capacity of dendritic cells to stimulate Mls-reactive T cell hybridomas and the primary anti-Mls mixed lymphocyte reaction. J Immunol, in press.

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    Daniel L. Hamilos

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Hamilos, D.L. Antigen presenting cells. Immunol Res 8, 98–117 (1989). https://doi.org/10.1007/BF02919073

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