Skip to main content
SpringerLink
Log in

Lipid metabolism and the initiation and regulation of mediator release from mast cells

  • Symposium
  • Published:
Survey of Immunologic Research Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

References

  1. Sullivan, T.J.; Kulczycki, A.: Immediate hypersensitivity responses; in Parker, Clinical immunology, pp. 115–142 (Saunders, London 1980).

    Google Scholar 

  2. Sullivan, T.J.; Parker, K.L.; Stenson, W.; Parker, C.W.: Modulation of cyclic AMP in purified rat mast cells. I. Responses to pharmacologic, metabolic, and physical stimuli. J. Immun.114: 1473–1479 (1975).

    PubMed  CAS  Google Scholar 

  3. Schulman, E.S.; MacGlashan, D.W.; Peters, S.P.; Schleimer, R.S.; Newball, M.M.; Lichtenstein, L.M.: Human lung mast cells: purification and characterization. J. Immun.129: 2662–2667 (1982).

    PubMed  CAS  Google Scholar 

  4. Holgate, S.T.; Church, M.K.: Control of mediator release from mast cells. Clin. Allergy12: suppl., pp.5–13 (1982).

    PubMed  CAS  Google Scholar 

  5. Redai, I.; Balazs, M.; Juszupova, S.: Changes in membrane fluidity of mast cells, induced by antigen-anaphylactic antibody reaction. Acta biochim. biophys. Acad. Sci. hung.14: 223–227 (1979).

    PubMed  CAS  Google Scholar 

  6. Kennedy, D.A.; Sullivan, T.J.; Parker, C.W.: Activation of phospholipid metabolism during mediator release from stimulated rat mast cells. J. Immun.122: 152–159 (1979).

    Google Scholar 

  7. Cockcroft, S.; Gomperts, B.D.: Evidence for a role of phosphatidylinositol turnover in stimulus-secretion coupling: studies with rat peritoneal mast cells. Biochem. J.178: 681–687 (1979).

    PubMed  CAS  Google Scholar 

  8. Michell, R.: Inositol lipids and cell surface receptor function. Biochim. biophys. Acta415: 81–140 (1975).

    PubMed  CAS  Google Scholar 

  9. Kennedy, D.A.; Secosan, C.J.; Parker, C.W.; Sullivan, T.J.: Modulation of stimulated phospholipid metabolism in mast cells by pharmacologic agents which increase cyclic 3′, 5′-adenosine monophosphate levels. J. Immun.123: 1519–1524 (1979).

    Google Scholar 

  10. Marquardt, D.L.; Nicolotti, R.A.; Kennedy, D.A.; Sullivan, T.J.: Metabolism during mediator release from mast cells: studies of the role of arachidonic acid metabolism in the control of phospholipid metabolism. J. Immun.127: 845–849 (1981).

    PubMed  CAS  Google Scholar 

  11. Fagan, D.L.· Sullivan, T.J.: Possible role of lysophosphatidic acid in antigen-induced mast cell mediator release. Fed. Proc. Abstr. No. 4636 (1983).

  12. Kennedy, D.A.; Sullivan, T.J.; Sylwester, P.; Parker, C.W.: Diacylglycerol metabolism in mast cells: a potential role in membrane fusion and arachidonic acid release. J. exp. Med.150: 1039–1044 (1979).

    Article  Google Scholar 

  13. Sullivan, T.J.: Studies of the roles of 1, 2 diacylglycerol in mast cell mediator release (in preparation, 1984).

  14. Lucy, J.A.: Mechanisms of chemically induced cell fusion; in Poste, Nicolson, Cell surface reviews, vol. 5: Membrane fusion, pp. 267–304 (Elsevier/North-Holland, Amsterdam 1978).

    Google Scholar 

  15. Sandier, R.; Papahadjopoulos, D.: Control of membrane fusion by phospholipid head groups. Biochim. biophys. Acta649: 743–750 (1981).

    Article  Google Scholar 

  16. Stenson, W.F.; Parker, C.W.; Sullivan, T.J.: Augmentation of IgE-mediated release of histamine by 5-hydroxyeicosatetraenoic acid and 12-hydroxyeicosatetraenoic acid. Biochem. biophys. Res. Commun.96: 1045–1052 (1980).

    Article  PubMed  CAS  Google Scholar 

  17. Serhan, C.; Anderson, P.; Goodman, E.; Dunham, P.; Weissmann, G.: Phosphatidate and oxidized fatty acids are calcium ionophores. J. biol. Chem.26: 2736–2741 (1981).

    Google Scholar 

  18. Nishizuka, Y.: Calcium, phospholipid transmembrane signalling. Phil. Trans. R. Soc. Lond. B302: 101–112 (1983).

    Article  CAS  Google Scholar 

  19. Russell, T.J.; Sullivan, T.J.: Possible role of protein kinase C in the release of mediators from mast cells (The University of Texas Southwestern Medical School Medical Student Research Forum 1983).

  20. Hempstead, B.L.; Parker, C.W.; Kulczycki, A.: Selective phosphorylation of the IgE receptor in antigen-stimulated rat mast cells. Proc. natn. Acad. Sci. USA80: 3050–3053 (1983).

    Article  CAS  Google Scholar 

  21. Martin, T.W.; Lagunoff, D.: Interactions of lysophospholipids and mast cells. Nature, Lond.279: 250–252 (1979).

    Article  CAS  Google Scholar 

  22. Tamori-Natori, Y.; Najima, S.: Activation of histamine secretion from rat mast cells by phosphatidylserine analogues resistant to phospholipase A action. J. Biochem., Tokyo91: 1825–1928 (1982).

    CAS  Google Scholar 

  23. Martin, T.W.; Lagunoff, D.: Inhibition of mast cell histamine secretion by N-substituted derivatives of phosphatidylserine. Science204: 631–632 (1979).

    Article  PubMed  CAS  Google Scholar 

  24. Martin, T.W.; Lagunoff, D.: Rat mast cell phospholipase A2: activity toward exogenous phosphatidylserine and inhibition by N-(7-nitro-2, 1, 3-ben-zoxadiazol-4-yl) phosphatidylserine. Biochemistry21: 1254–1260 (1982).

    Article  PubMed  CAS  Google Scholar 

  25. Hirata, F.; Axelrod, J.; Crews, F.T.: Concanavalin A stimulates phospholipid methylation and phosphatidylserine decarboxylation in rat mast cells. Proc. natn. Acad. Sci. USA76: 4913–4916 (1979).

    Article  Google Scholar 

  26. Ishizaka, T.; Hirata, F.; Ishizaka, K.; Axelrod, J.: Stimulation of phospholipid methylation, Ca2+ influx, and histamine release by binding of IgE receptors on rat mast cells. Proc. natn. Acad. Sci. USA77: 1903–1906 (1980).

    Article  CAS  Google Scholar 

  27. Hirata, F.; Axelrod, J.: Enzymatic synthesis and rapid translocation of phosphatidylcholine by two methyltransferases in erythrocyte membranes. Proc. natn. Acad. Sci. USA75: 2348–2352 (1978).

    Article  CAS  Google Scholar 

  28. Ishizaka, T.; Hirata, F.; Sterk, A.; Ishizaka, K.; Axelrod, J.A.: Bridging of IgE receptors activates phospholipid methylation and adenylate cyclase in mast cell plasma membranes. Proc. natn. Acad. Sci. USA78: 6812–6816 (1981).

    Article  CAS  Google Scholar 

  29. Standberg, K.; Westerberg, S.: Composition of phospholipids and phospholipid fatty acids in rat mast cells. Mol. Cell Biochem.11: 103–107 (1976).

    Article  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Internal Medicine, University of Texas Health Science Center, 5323 Harry Hines Boulevard, 75235, Dallas, TX, USA

    Donald A. Kennerly

Authors
  1. Donald A. Kennerly
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Kennerly, D.A. Lipid metabolism and the initiation and regulation of mediator release from mast cells. Surv. immunol. Res. 3, 304–310 (1984). https://doi.org/10.1007/BF02919048

Download citation

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02919048

Keywords

Search

Navigation