This is a preview of subscription content, log in via an institution to check access.
References
Bretscher MS: The molecules of the cell membrane. Sci Am 1985; 253: 100–109.
Kaufman JF, Uffray C, Korman AJ, Shackelford DA, Strominger J: The class II molecules of the human and murine major histocompatibility complex. Cell 1984; 36: 1.
Kappes D, Strominger JL: Human class II major histocompatibility complex genes and proteins; in Richardson C. (ed): Annual Review of Biochemistry. Palo Alto, Annual Reviews, 1988, vol 57, pp 991–1028.
Charron DJ, McDevitt HO: Characterization of HLA-D region antigens by two-dimensional gel electrophoresis. Molecular genotyping. J Exp Med 1980; 152: 365.
Auffray C, Strominger JL: Molecular genetics of the human histocompatibility complex. Adv Hum Genet 1986; 15: 197.
Goyert SM, Silver J: Further characterization of HLA-DS molecules: Implications for studies assessing the role of human Ia molecules in cell interactions and disease susceptibility. Proc Natl Acad Sci USA 1983; 80: 5719–1722.
Lotteau V, Teyton L, Tongio MM, Soulier A, Thomsen M, Sasportes M, Charron D: Biochemical polymorphism of the HLA-DP heavy chain. Immunogenetics 1987; 25: 403–407.
Charron D, Lotteau V, Turmel P: Hybrid HLA-DC antigens provide molecular evidence for gene transcomplementation. Nature 1984; 312: 157–160.
Nepom BS, Schwartz D, Palmer JP, Nepom GT: Transcomplementation of HLA genes in IDDM. Diabetes 1987; 36: 114.
Charron D: The molecular basis of HLA class II disease associations. Adv Immunol, in press, 1990.
Travers P, Blundell TL, Sternberg MJE, Bodmer WF: Structural and evolutionary analysis of HLA-D region products. Nature 1984; 310: 235.
Norcross MA, Raghupathy R, Strominger L, Germain RN: Transfected human B lymphoblastoid cells express the mouse IA βd chain in association with DR α. J Immunol 1986; 137: 1714.
Germain RN, Quill H: Unexpected expression of a unique mixed-idotype class II MHC molecule by transfected L cells. Nature 1986; 320: 72.
Lotteau V, Teyton L, Burroughs D, Charron D: A novel HLA class II molecule (DRα-DQβ) created by mismatched isotype pairing. Nature 1987; 329: 339–341.
Piatier-Tonneau D, Turmel P, Auffray C, Charron D: Construction of chain and locus specific HLA class II DNA probes. Study of HLA class II transcripts in leukemia. J Immunol 1986; 137: 2050–2056.
Lotteau V, Sands J, Teyton L, Turmel P, Charron D, Strominger J: Modulation of HLA class II antigen expression by transfection of sense and antisense DRα cDNA. J Exp Med 1989; 169: 351–356.
Sant AJ, Germain RN: Intracellular competition for component chains determines class II MHC cell surface phenotype. Cell 1989; 57: 797.
Brown JH, Jardetzky T, Saper MA, Samraoui B, Bjorkman P, Wiley DC: A hypothetical model of the foreign antigen binding site of class II histocompatibility molecules. Nature 1988; 332: 845.
Bjorkman PJ, Saper MA, Samraoui B, Bennet WS, Strominger JL, Wiley DC: Structure of the human class I histocompatibility antigen, HLA-A2. Nature 1987; 329: 506–512.
Kyte J, Doolittle RF: A simple method for displaying the hydropathic character of a protein. J Mol Biol 1982; 157: 105–132.
Heyes J, Austin P, Bodmer J, Bodmer W, Madrigal A, Mazzili MC, Trowsdale J: Monoclonal antibodies to HLA-DP transfected mouse L cells. Proc Natl Acad Sci USA 1986; 83: 3417–3421.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Charron, D.J., Hermans, P., Lotteau, V. et al. Interisotypic α- and β-chain assembly as a source of HLA class-II diversity. Immunol Res 9, 234–243 (1990). https://doi.org/10.1007/BF02918182
Issue Date:
DOI: https://doi.org/10.1007/BF02918182