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Regional differences in immune regulation: The immunogenic privilege of corneal allografts

Immunologic Research volume 7, pages 247–255 (1988)Cite this article

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References

  1. Silverstein, A.M.; Khoudadoust, A.A.: Transplantation immunobiology of the cornea; in Porter, Knight, Corneal graft failure, pp. 105–125 (Elsevier/North Holland, Amsterdam 1973).

    Chapter  Google Scholar 

  2. Billingham, R.E.; Boswell, T.: Studies on the problem of corneal homografts. Proc. R. Soc.141: 392–406 (1953).

    CAS  Google Scholar 

  3. Khodadoust, A.A.; Silverstein, A.M.: Studies on the heterotopic transplantation of cornea of the skin. Surv. Ophthal.11: 435–443 (1966).

    CAS  Google Scholar 

  4. Chandler, J.W.; Ray-Keil, L.; Gillette, T.E.: Experimental corneal allograft rejection: description of murine model and a new hypothesis of immunopathogenesis. Curr. Eye Res.2: 387–397 (1983).

    Article  CAS  Google Scholar 

  5. Streilein, J.W.; McCulley, J.; Niederkorn, J.Y.: Heterotopic corneal grafting in mice: a new approach to the study of corneal alloimmunity. Investve Ophthal. vis. Sci.23: 489–500 (1982).

    CAS  Google Scholar 

  6. Mayer, D.J.; Daar, A.S.; Casey, T.A.; Fabre, J.W.: Localization of HLA-A,B,C and HLA-DR antigens in the human cornea. Practical significance for grafting technique and HLA typing. Transplant. Proc.15: 126–129 (1983).

    Google Scholar 

  7. Whitsett, C.F.; Stulting, R.D.: The distribution of HLA antigens on human corneal tissue. Investve Ophthal. vis. Sci.25: 519–524 (1984).

    CAS  Google Scholar 

  8. Manski, W.; Whiteside, T.L.: Cell-surface receptors of normal regenerating and cultured corneal epithelial and endothelial cells. Investve Ophth.13: 935–955 (1974).

    CAS  Google Scholar 

  9. Treseler, P.A.; Foulks, G.N.; Sanfilippo, F.: The expression of HLA antigens by cells in the human cornea. Am. J. Ophthal.98: 763–772 (1984).

    PubMed  CAS  Google Scholar 

  10. Khodadoust, A.A.; Silverstein, A.M.: Transplantation and rejection of individual cell layers of the cornea. Investve Ophth.8: 180–195 (1969).

    CAS  Google Scholar 

  11. Khodadoust, A.A.; Silverstein, A.M.: The survival and rejection of epithelium in experimental corneal transplants. Ophthalmology8: 169–179 (1969).

    CAS  Google Scholar 

  12. Khodadoust, A.A.; Silverstein, A.M.: Studies on the nature of the privilege enjoyed by corneal allografts. Investve Ophth.11: 137–148 (1972).

    CAS  Google Scholar 

  13. Treseler, P.A.; Foulks, G.N.; Sanfilippo, F.: The relative immunogenicity of corneal epithelium, stroma, and endothelium. Transplantation41: 229–234 (1986).

    PubMed  CAS  Google Scholar 

  14. Treseler, P.A.; Sanfilippo, F.: The expression of major histocompatibility complex and leukocyte antigens by cells in the rat cornea. Transplantation41: 248–252 (1986).

    PubMed  CAS  Google Scholar 

  15. Basu, P.K.; Miller, I.; Ormsby, H.L.: Sex chromatin as a biologic cell marker in the study of the fate of corneal transplants. Am. J. Ophthal.49: 513–515 (1960).

    PubMed  CAS  Google Scholar 

  16. Chi, H.H.; Teng, C.C.; Katzin, H.M.: The fate of endothelial cells in corneal homografts. Ophthalmology59: 186–191 (1965).

    CAS  Google Scholar 

  17. Hanna, C.; Irwin, E.S.: Fate of cells in the corneal graft. Archs Ophthal.68: 810–817 (1962).

    Google Scholar 

  18. Polack, F.M.; Smelser, G.K.; Rose, J.: Long-term survival of isotopically labelled stromal and endothelial cells in corneal homografts. Am. J. Ophthal.57: 67–78 (1964).

    PubMed  CAS  Google Scholar 

  19. Khodadoust, A.A.: The allograft rejection reaction. The leading cause of late failure of clinical corneal grafts; in Porter, Knight, Corneal graft failure, pp. 151–167 (Elsevier/North Holland, Amsterdam 1973).

    Chapter  Google Scholar 

  20. Batchelor, J.R.; Casey, T.A.; Gibbs, D.C.; Lloyd, D.F.; Werb, A.; Prasad, S.S.; James, A.: HLA matching and corneal grafting. Lanceti: 551–554 (1976).

    Article  Google Scholar 

  21. Maumenee, A.E.: The influence of donor-recipient sensitization on corneal grafts. Am. J. Ophthal.34: 142–152 (1951).

    PubMed  CAS  Google Scholar 

  22. Callanan, D.; Peeler, J.; Niederkorn, J.Y.: Characteristics of rejection of orthotopic corneal allografts in the rat. Transplantation (in press, 1988).

  23. Khodadoust, A.A.: Penetrating keratoplasty in the rabbit. Am. J. Ophthal.66: 899–905 (1968).

    PubMed  CAS  Google Scholar 

  24. Braude, L.S.; Chandler, J.W.: Corneal allograft rejection. The role of the major histocompatibility complex. Surv. Ophthal.27: 290–305 (1983).

    Article  CAS  Google Scholar 

  25. Vantrappen, L.; Geboes, K.; Missotten, L.; Maudgal, P.C.; Desmet, V.: Lymphocytes and Langerhans cells in the normal human cornea. Investve Ophthal. vis. Sci.26: 220–225 (1985).

    CAS  Google Scholar 

  26. Rodriguez, M.M.; Rowden, G.; Hackett, J.; Bakos, I.: Langerhans cells in the normal conjunctiva and peripheral cornea of selected species. Investve Ophthal. vis. Sci.21: 759–765 (1981).

    Google Scholar 

  27. Chandler, J.W.; Cummings, M.; Gillette, T.E.: Presence of Langerhans cells in the central corneas of normal human infants. Investve Ophthal. vis. Sci.26: 113–116 (1985).

    CAS  Google Scholar 

  28. Seto, S.K.; Gillette, T.E.; Chandler, J.W.: HLA-DR+/T6-Langerhans cells of the human cornea. Investve Ophthal. vis. Sci.28: 1719–1722 (1987).

    CAS  Google Scholar 

  29. Rubsamen, P.E.; McCulley, J.; Bergstresser, P.R.; Streilein, J.W.: On the Ia immunogenicity of mouse corneal allografts infiltrated with Langerhans cells. Investve Ophthal. vis. Sci.25: 513–518 (1984).

    CAS  Google Scholar 

  30. Streilein, J.W.; Towes, G.B.; Bergstresser, P.R.: Corneal allografts fail to express Ia antigens. Nature282: 326–327 (1979).

    PubMed  Article  CAS  Google Scholar 

  31. Peeler, J.S.; Niederkorn, J.Y.: Antigen presentation by Langerhans cells in vivo: donor-derived Ia+Langerhans cells are required for induction of delayed-type hypersensitivity but not for cytotoxic T lymphocyte responses to alloantigens. J. Immun.136: 4362–4371 (1986).

    PubMed  CAS  Google Scholar 

  32. Lafferty, K.J.; Prowse, S.J.; Silmenonvic, C.J.; Warren, H.S.: Immunobiology of tissue transplantation: a return to the passenger cell concept. Annu. Rev. Immunol.1: 143 (1983).

    PubMed  Article  CAS  Google Scholar 

  33. Snell, G.D.: The homograft reaction. A. Rev. Microbiol.11: 439–458 (1957).

    Article  CAS  Google Scholar 

  34. Ray-Keil, L.; Chandler, J.W.: Reduction in the incidence of rejection of heterotopic murine corneal transplants by pretreatement with ultraviolet radiation. Transplantation42: 403–406 (1986).

    PubMed  Article  CAS  Google Scholar 

  35. Ray-Keil, L.; Chandler, J.W.: Rejection of murine heterotopic corneal transplants. Transplantation39: 473–477 (1985).

    PubMed  CAS  Article  Google Scholar 

  36. Matoba, A.Y.; Peeler, J.S.; Niederkorn, J.Y.: T cell subsets in the immune rejection of murine heterotopic corneal allografts. Investve Ophthal. vis. Sci.27: 1244–1254 (1986).

    CAS  Google Scholar 

  37. Peeler, J.S.; Niederkorn, J.Y.; Matoba, A.: Corneal allografts induce cytotoxic T cell but not delayed hypersensitivity responses in mice. Investve Ophthal. vis. Sci.26: 1516–1523 (1985).

    CAS  Google Scholar 

  38. Peeler, J.S.; Niederkorn, J.Y.: Effect of Langerhans cells on cytotoxic T lymphocyte responses to major and minor alloantigens expressed on heterotopic corneal allografts. Transplant. Proc.19: 316–319 (1987).

    PubMed  CAS  Google Scholar 

  39. Donnelly, J.J.; Li, W.; Rockey, J.H.; Prendergast, R.A.: Induction of class II (Ia) alloantigen expression on corneal endothelium in vivo and in vitro. Investve Ophthal. vis. Sci.26: 575–580 (1985).

    CAS  Google Scholar 

  40. Young, E.; Stark, W.J.; Prendergast, R.A.: Immunology of corneal allograft rejection: HLA-DR antigens on human corneal cells. Investve Ophthal. vis. Sci.26: 571–574 (1985).

    CAS  Google Scholar 

  41. Williamson, J.S.P.; DiMarco, S.: Streilein, J.W.: Immunobiology of Langerhans cells on the ocular surface. Investve Ophthal. vis. Sci.28: 1527–1532.

  42. Grabner, G.; Luger, T.A.; Luger, B.M.; Smolin, G.; Oh, J.O.: Biologic properties of the thymocyte-activating factor (CETAF) produced by a rabbit corneal cell line (SIRC). Investve Ophthal. vis. Sci.24: 589–595 (1983).

    CAS  Google Scholar 

  43. Miossec, P.; Ye, C.-L.; Ziff, M.: Lymphocyte chemotactic activity of human interleukin 1. J. Immun.133: 2007–2011 (1984).

    PubMed  CAS  Google Scholar 

  44. Lasser, A.: The mononuclear phagocytic system: a review. Human Pathol.14: 108–126 (1983).

    CAS  Article  Google Scholar 

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Affiliations

  1. Research to Prevent Blindness-Olga Keith Wiess Scholar, Department of Ophthalmology, University of Texas Southwestern Medical Center at Dallas, 75235, Dallas, TX, (USA)

    Jerry Y. Niederkorn & John S. Peeler

  2. Research to Prevent Blindness-Olga Keith Wiess Scholar, Department of Cell Biology and Anatomy, University of Texas Southwestern Medical Center, Dallas, Tex., USA

    Jerry Y. Niederkorn & John S. Peeler

Authors
  1. Jerry Y. Niederkorn
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  2. John S. Peeler
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Niederkorn, J.Y., Peeler, J.S. Regional differences in immune regulation: The immunogenic privilege of corneal allografts. Immunol Res 7, 247–255 (1988). https://doi.org/10.1007/BF02918140

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  • DOI: https://doi.org/10.1007/BF02918140

Keywords

  • Corneal Epithelium
  • Corneal Epithelial Cell
  • Corneal Graft
  • Corneal Allograft
  • Corneal Allograft Rejection