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Alteration of spermatozoal structure and trace metal profile of testis and epididymis of rat under chronic low-level X-ray irradiation

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Abstract

This study investigates the short-term as well as long-term effects of low-level X-ray irradiation on the Spermatozoal structure and trace metal (Zn, Fe, Cu, and Cd) contents in the testis and epididymis of whole-body irradiated albino rats. Male rats were exposed to 0.675, 1.350, 2.700, and 4.050 cGy of X-ray intermittently in 45, 90 180, and 270 equal fractions (each fraction of 0.015 cGy s−1), respectively. SEM study had revealed numerous fusiform swelling in sperm tail in most of the x-irradiated groups. Moreover, in 2.700 and 4.050 cGy dose groups, the tail sheath of several sperm were eroded out. In the TEM study, damage in microtubules of sperm tail in 4.050 cGy irradiated group was noted. The AAS study showed a transient increase in Zn content in 0.675 and 1.350 cGy dose groups, but its concentration was decreased in 2.700 and 4.050 cGy dose groups. Fe concentration was increased in all the cases in comparison to that of control group. Nevertheless, Cu and Cd contents were increased mostly in 2.700 and 4.050 cGy doses. Thus present findings probably throw some light regarding mammalian response threshold at low-level X-ray irradiation. Moreover, it raises questions regarding the validity of “safe dose ionizing radiation.”

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Authors and Affiliations

  1. Department of Anatomy, Burdwan Medical College, Burdwan, West Bengal, India

    J. Chatterjee & S. K. Basu

  2. Department of Chemistry, University of Burdwan, 713 104, Burdwan, West Bengal, India

    K. De & A. K. Das

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  1. J. Chatterjee
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  2. K. De
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  3. S. K. Basu
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  4. A. K. Das
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Chatterjee, J., De, K., Basu, S.K. et al. Alteration of spermatozoal structure and trace metal profile of testis and epididymis of rat under chronic low-level X-ray irradiation. Biol Trace Elem Res 41, 305–319 (1994). https://doi.org/10.1007/BF02917431

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  • DOI: https://doi.org/10.1007/BF02917431

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