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Gallium distribution in several human brain areas

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Abstract

Gallium is an element of increasing biological interest: It is involved in problems related to environmental pollution (Ga compounds are used in electronics industry) and to clinical treatments (Ga radionuclides are employed to detect neoplastic lesions). Moreover, since its chemical behavior is similar to that of aluminum, gallium could play a role in the health effects attributed to this element.

Data on naturally occurring Ga levels in human samples from healthy subjects are scanty; regarding the brain, the only reliable values available in the literature were published by Hamilton in 1972/73. In this work, the gallium distribution in several human brain areas, evaluated by radiochemical neutron activation analysis (RNAA), was found to be dishomogeneous. The element concentration determined in dry samples was, in any case, lower than the ppb level.

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Authors and Affiliations

  1. CNR Centro di studio per la Radiochimica e l'Analisi per Attivazione, Universita' di Pavia, 27100, Pavia, Italy

    Margherita Speziali, Edoardo Orvini & Enrico Rizzio

  2. Ospedale Civile, 30015, Chioggia (VE), Italy

    Renzo Giordano

  3. CNR Centro di studio per la Fisiologia e la Biochimica delle Emocianine e di altre Metallo-proteine, Universita' di Padova, 35131, Padova, Italy

    Paolo Zatta

  4. Dept. Biology, Univ. Padova, via Loredan 10, 35131, Padova, Italy

    M. Favarato & M. Perazzolo

Authors
  1. Margherita Speziali
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  2. Edoardo Orvini
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  3. Enrico Rizzio
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  4. Renzo Giordano
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  5. Paolo Zatta
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  6. M. Favarato
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  7. M. Perazzolo
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Speziali, M., Orvini, E., Rizzio, E. et al. Gallium distribution in several human brain areas. Biol Trace Elem Res 22, 9–15 (1989). https://doi.org/10.1007/BF02917412

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  • DOI: https://doi.org/10.1007/BF02917412

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