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Use of total Reflection X-ray Fluorescence Analysis in the life sciences

  • Methodology of Nuclear Analytical Methods
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Abstract

Total Reflection X-ray Fluorescence Analysis (TXRF) is accepted as a powerful analytical tool. TXRF is basically an energy-dispersive technique with the sample excitated in total reflection geometry. Simultaneous detection of almost all chemical elements and lower limits of detection for medium Z elements in the range of a few hundred fg are achievable at optimized excitation conditions. Aqueous and acidic solutions are the preferred sample types, so a lot of applications in the life sciences are given. For solids and other samples, special preparation techniques are required.

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Wobrauschek, P. Use of total Reflection X-ray Fluorescence Analysis in the life sciences. Biol Trace Elem Res 43, 65–71 (1994). https://doi.org/10.1007/BF02917300

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  • DOI: https://doi.org/10.1007/BF02917300

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