Abstract
Three experiments were conducted investigating the interaction of dietary vanadate and mercury on the growth of chicks. The growth-retarding effect of 30 mg vanadium/kg diet was completely overcome by the inclusion of 500 mg mercury/kg diet. Restricting the feed intake of the mercury-supplemented animals to approximately those receiving vanadate alone still resulted in an amelioration of the growth retarding effect of vanadate. Analyses of femurs and kidneys revealed that mercury added to a vanadium-containing diet increased the vanadate concentration of the femur and had no effect on the vanadium concentration in the kidney. As little as 25 mg mercury/kg diet significantly reduced the growth retarding effect of vanadium. The inclusion of 100 mg mercury/kg in the diet resulted in a significant increase in renal glutathione concentration.
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Paper No. 11867 of the Journal Series of the NC Agricultural Research Service, Raleigh, NC 27695-7643. The use of trade names implies neither endorsement of the products named nor criticism of similar products not mentioned by the NCARS.
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Hill, C.H. The effect of dietary mercury on vanadate toxicity in the chick. Biol Trace Elem Res 23, 11–16 (1989). https://doi.org/10.1007/BF02917174
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DOI: https://doi.org/10.1007/BF02917174