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Zinc concentration in erythrocyte membranes in normal volunteers and in patients with taste and smell dysfunction

Biological Trace Element Research volume 5, pages 1–8 (1983)Cite this article

Abstract

Erythrocyte membrane zinc concentration was measured in 14 normal volunteers and in 36 patients with taste and smell dysfunction, and compared with zinc concentration in erythrocyte cytosol and blood plasma in the normal volunteers and with zinc concentration in erythrocyte cytosol, blood serum, urine, and parotid saliva in the patients. A A significant negative correlation was found between age and membrane zinc concentration in the normals. A significant positive correlation was found between parotid saliva zinc and erythrocyte membrane zinc concentrations in the patients. Concentration of zinc in the erythrocyte membrane is 50% greater than its concentration in cytosol, and three times greater than the zinc concentration in plasma or serum; membrane zinc concentration in humans is approximately one-half that reported in the dog or in the mouse.

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Affiliations

  1. Center for Molecular Nutrition and Sensory Disorders, Georgetown University Medical Center, 20007, Washington, DC

    P. L. McWilliams, R. P. Agarwal & R. I. Henkin

Authors
  1. P. L. McWilliams
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  2. R. P. Agarwal
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  3. R. I. Henkin
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McWilliams, P.L., Agarwal, R.P. & Henkin, R.I. Zinc concentration in erythrocyte membranes in normal volunteers and in patients with taste and smell dysfunction. Biol Trace Elem Res 5, 1–8 (1983). https://doi.org/10.1007/BF02916921

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  • DOI: https://doi.org/10.1007/BF02916921

Index Entries

  • Zinc in erythrocyte membranes
  • trace metals, and erythrocytes
  • zinc deficiency, and taste and smell dysfunction
  • taste dysfunction, and zinc deficiency
  • smell dysfunction, and zinc deficiency
  • erythrocyte zinc concentration, and taste and smell dysfunction
  • membranes, zinc concentration in erythrocyte