Skip to main content
SpringerLink
Log in

Dietary zinc and parturition in the rat

I. Uterine pressure cycles

  • Original Articles
  • Published:
Biological Trace Element Research Aims and scope Submit manuscript

Abstract

The pattern of uterine pressure cycles following oxytocin infusion was evaluated in near-term pregnant rats as a function of dietary zinc. Pressure cycles were monitored by a pressure transducer and polygraph linked to an intrauterine water-filled latex balloon, inserted on d 19 of gestation, in place of the right cranial fetus and its placenta. Oxytocin infusion on d 22 induced labor in all five zincdeficient rats, but the tracings revealed irregular, poorly synchronized, and/or low amplitude patterns, compared to controls. Excessive abdominal straining was required to accomplish fetal emergence in many instances. The results are interpreted as suggestive of diminished gap-junction formation.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Similar content being viewed by others

References

  1. J. Apgar,Am. J. Physiol. 215, 160 (1968).

    PubMed  CAS  Google Scholar 

  2. A. Eklund,Nutr. Rep. Int. 7, 647 (1973).

    CAS  Google Scholar 

  3. A. Eklund,Nutr. and Metab. 19, 173 (1975).

    CAS  Google Scholar 

  4. J. M. McLaughlan, J. D. Jones, B. G. Shah, and J. L. Beare-Rogers,Nutr. Rep. Int. 11, 327 (1975).

    CAS  Google Scholar 

  5. G. H. Anderson, L. Harris, A. V. Rao, and J. D. Jones,J. Nutr. 106, 1166 (1976).

    PubMed  CAS  Google Scholar 

  6. B. L. O’Dell, G. Reynolds, and P. G. Reeves,J. Nutr. 107, 1222 (1977).

    PubMed  CAS  Google Scholar 

  7. J. Apgar,Am. J. Physiol. 215, 1478 (1968).

    PubMed  CAS  Google Scholar 

  8. J. Apgar,J. Nutr. 105, 1553 (1975).

    PubMed  CAS  Google Scholar 

  9. J. Apgar,J. Nutr. 103, 973 (1973).

    PubMed  CAS  Google Scholar 

  10. G. E. Bunce, G. R. Wilson, C. F. Mills, and A. Klopper,Biochem. J. 210, 761 (1983).

    PubMed  CAS  Google Scholar 

  11. A.-R. Fuchs and V. F. Poblete, Jr.,Biol. Reprod. 2, 387 (1970).

    Article  PubMed  CAS  Google Scholar 

  12. O. D. Sherwood, V. E. Crnekovic, W. L. Gordon, and J. E. Rutherford,Endocrinology 107, 691 (1980).

    Article  PubMed  CAS  Google Scholar 

  13. E. J. Pavlik, P. B. Coulson,J. Steroid Biochem. 7, 357 (1976).

    Article  PubMed  CAS  Google Scholar 

  14. D. W. Lincoln and D. G. Porter,Anim. Reprod. Sci. 2 97 (1979).

    Article  Google Scholar 

  15. R. E. Garfield, S. M. Sims, M. S. Kannan, and E. E. Daniel,Am. J. Physiol. 235, C168 (1978).

    PubMed  CAS  Google Scholar 

  16. S. M. Sims, E. E. Daniel, and R. E. Garfield,J. Gen Physiol. 80, 353 (1982).

    Article  PubMed  CAS  Google Scholar 

  17. E. E. Daniel, S. Fair, A. M. Kidwai, and I. Polacek,J. Pharmacol. Exptl. Therapeu.,178, 282 (1971).

    CAS  Google Scholar 

  18. E. E. Daniel, S. Fair, and A. M. Kidwai,J. Pharmacol. Exp. Ther. 178, 290 (1971).

    PubMed  CAS  Google Scholar 

  19. D. P. Dylewski, F. D. C. Lytton, and G. E. Bunce,Biol. Trace Elem. Res. in press, (1985).

  20. G. Shyamala and Y.-F. Yeh,Biochem. Biophys. Res. Comm. 64, 408 (1975).

    Article  PubMed  CAS  Google Scholar 

  21. P. H. Lohmar and D. O. Toft,Biochem. Biophys. Res. Comm. 67, 8 (1975).

    Article  PubMed  CAS  Google Scholar 

  22. D. S. Colvard and E. M. Wilson,Biochemistry 23, 3471 (1984).

    Article  PubMed  CAS  Google Scholar 

  23. J. P. Slater, A. S. Mildvan, and L. A. Loeb,Biochem. Biophys. Res. Commn. 44, 37 (1971).

    Article  CAS  Google Scholar 

  24. K. H. Falchuk, B. Mazus, L. Ulpino, and B. L. Vallee,Biochemistry 15, 4468 (1976).

    Article  PubMed  CAS  Google Scholar 

  25. B. J. Poiesz, G. Seal, and L. A. Loeb,Proc. Nat. Acad. Sci. USA 71 4892 (1974).

    Article  PubMed  CAS  Google Scholar 

  26. J. K. Barton, L. A. Basile, and S. R. Paranawithana,J. Biol. Chem. 257, 7911 (1982).

    PubMed  CAS  Google Scholar 

  27. V. M. Vogt,Eur. J. Biochem. 33, 192 (1973).

    Article  PubMed  CAS  Google Scholar 

  28. A. S. Prasad, A. Miale, Jr., Z. Farid, H. H. Sandstead, A. R. Schulert, and W. J. Darby,AMA Arch. Int. Med. 111, 407 (1963).

    CAS  Google Scholar 

  29. R. D. Lindeman, R. G. Bottomley, R. L. Cornelison, and L. A. Jacobs,J. Lab. Clin. Med. 79, 452 (1972).

    PubMed  CAS  Google Scholar 

  30. T. Durá-Travé, M. Puig-Abuli, I. Monreal, and I. Villa-Elizaga,Gynecol. Obstet. Invest. 17, 247 (1984).

    Article  PubMed  Google Scholar 

Download references

Author information

Authors and Affiliations

  1. Department of Biochemistry and Nutrition, Virginia Polytechnic Institute and State University, 24061, Blacksburg, VA

    Fiona D. C. Lytton & G. E. Bunce

Authors
  1. Fiona D. C. Lytton
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. G. E. Bunce
    View author publications

    You can also search for this author in PubMed Google Scholar

Rights and permissions

Reprints and permissions

About this article

Cite this article

Lytton, F.D.C., Bunce, G.E. Dietary zinc and parturition in the rat. Biol Trace Elem Res 9, 151–163 (1986). https://doi.org/10.1007/BF02916523

Download citation

  • Received:

  • Accepted:

  • Issue Date:

  • DOI: https://doi.org/10.1007/BF02916523

Index Entries

Search

Navigation