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Primary low-grade B-cell lymphoma in mucosa-associated lymphoid tissue of the lung

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Abstract

A67-year-old asymptomatic woman was referred to our department for treatment for a left lung tumor. The tumor was 40 mm in diameter and was present in the left lower lobe. A primary low-grade B-cell lymphoma in the mucosa-associated lymphoid tissue of the lung was suspected after a trans-bronchial lung tissue biopsy. Systemic screening revealed no other organ involvement, and the tumor was considered to be a primary lung tumor. A left lower lobectomy with hilar and mediastinal lymph node sampling was performed. Pathological examination revealed centrocyte-like cells that expressed CD20. These cells had invaded the bronchiolar epithelium to form lymphoepithelial lesions. The pathological diagnosis was confirmed to be primary low-grade B-cell lymphoma in the mucosa-associated lymphoid tissue of the lung. The origin of this tumor type in the lung is relatively rare.

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Murakawa, T., Nakajima, J., Tanaka, M. et al. Primary low-grade B-cell lymphoma in mucosa-associated lymphoid tissue of the lung. Jpn J Thorac Caridovasc Surg 49, 621–624 (2001). https://doi.org/10.1007/BF02916227

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  • DOI: https://doi.org/10.1007/BF02916227

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