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New directions in liposome gene delivery

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Abstract

The history of liposomes, progress in liposome gene delivery, and future directions are discussed. Specific characteristics of liposomes and DNA:liposome complexes have been identified that are essential for optimal delivery and gene expression. Of particular interest are the requirements for increased delivery and high levels of gene expression in vivo. At present, significant efforts are focused towards achieving specific delivery and gene expression in target organs and tissues.

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Authors and Affiliations

  1. Baylor College of Medicine, Center for Cell and Gene Therapy, One Baylor Plaza, BCM 505, 77030, Houston, TX

    Nancy Smyth Templeton

  2. Liposome Consultations, 7512 Birkdale Drive, 94560, Newark, CA

    Danilo D. Lasic

Authors
  1. Nancy Smyth Templeton
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  2. Danilo D. Lasic
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Corresponding authors

Correspondence to Nancy Smyth Templeton or Danilo D. Lasic.

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Templeton, N.S., Lasic, D.D. New directions in liposome gene delivery. Mol Biotechnol 11, 175–180 (1999). https://doi.org/10.1007/BF02915810

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  • DOI: https://doi.org/10.1007/BF02915810

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