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Evaluation of dopexamine hydrochloride as an anti-hypertensive agent after cardiac surgery

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International journal of clinical monitoring and computing

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References

  1. Taylor KM, Morton IJ, Brown JJ, Bain WH, Caves PK. Hypertension and the renin-angiotensin system following open heart surgery. Journal of Thoracic and Cardiovascular Surgery 1977; 74: 840–5.

    PubMed  CAS  Google Scholar 

  2. Estafanous FG, Tarazi RC, Viljoen JF, Tawil MY. Systemic hypertension following myocardial revascularisation. American Heart Journal 1973; 85: 732–8.

    Article  PubMed  CAS  Google Scholar 

  3. Roberts AJ, Niarchos AP, Subramanian VA, Abel RM, Herman SD, Sealey JE, Case DA, White RP, Johnson GA, Laragh JH, Gay WA Jr. Systemic hypertension associated with coronary artery bypass surgery. Journal of Thoracic and Cardiovascular Surgery 1977; 74: 846–59.

    PubMed  CAS  Google Scholar 

  4. Estafanous FG, Tarazi RC. Systemic hypertension associated with cardiac surgery. The American Journal of Cardiology 1980; 46: 685–94.

    Article  PubMed  CAS  Google Scholar 

  5. Wallach R, Karp RB, Reves JG et al. Pathogenesis of paroxysmal hypertension developing during and after coronary bypass surgery: A study of hemodynamic and humoral factors. The American Journal of Cardiology 1980; 46: 559–65.

    Article  PubMed  CAS  Google Scholar 

  6. Chiariello M, Gold HK, Leinbach RC, Davis MA, Maroko PR. Comparison between the effects of nitroprusside and nitroglycerin on ischemic injury during acute myocardial infarction. Circulation 1976; 54: 766–73.

    PubMed  CAS  Google Scholar 

  7. Becket LC. Conditions for vasodilator induced coronary artery steal in experimental myocardial ischemia. Circulation 1978; 57: 1103–10.

    Google Scholar 

  8. Colley PS, Cheney FW. Sodium nitroprusside increases Qs/Qt in dogs with regional atelectasis. Anesthesiology 1977;47: 338–41.

    Article  PubMed  CAS  Google Scholar 

  9. Azar I, Turndoff H. Intravenous nitroglycerin and pulmonary shunting after coronary artery bypass operation. American Review of Respiratory Disease 1979; 119: Suppl. 92.

    Google Scholar 

  10. Michenfelder JD. Cyanide release from sodium nitroprusside in the dog. Anesthesiology 1977; 46: 196–201.

    PubMed  CAS  Google Scholar 

  11. Ivankovitch AD, Miletich DJ, Tinker JH. Sodium nitroprusside: Metabolism and general considerations. International Anesthesiology Clinics 1978; 16: 1–29.

    Article  Google Scholar 

  12. Brown RA, Dixon J, Farmer JB, Hall JL, Humphries RL, Ince F, O’Connor SE, Simpson WT, Smith GW. Dopexamine: A novel agonist at peripheral dopamine receptors and β2-adrenoceptors. British Journal of Pharmacology 1985; 599–600.

  13. Magrini F, Foulds R, Roberts N, Macchi G, Mondadori C, Zanchetti H. Human renovascular effects of dopexamine hydrochloride; A novel agonist at peripheral dopamine and beta-2 adrenoreceptors. European Journal of Clinical Pharmacology 1987; 32(1): 1–4.

    Article  PubMed  CAS  Google Scholar 

  14. Mitchell PD, Smith GW, Wells E, West PA. Inhibition of Uptake-1 by dopexamine hydrochloride (in vitro). British Journal of Pharmacology 1987; 92: 265–70.

    PubMed  CAS  Google Scholar 

  15. Jaski BE, Wijns W, Foulds SR, Serruys PW. The haemodynamic and myocardial effects of dopexamine; a new β2-adrenoceptor agonist. British Journal of Clinical Pharmacology 1986; 21: 393–400.

    PubMed  CAS  Google Scholar 

  16. Neale MG, Baker P, Brown K, Foulds RA, Morris DA. Pharmacokinetics and metabolism of dopexamine in man. Acta Pharmacologica Toxicology 1986; 59(55): 69.

    Google Scholar 

  17. Tan LB, Littler W, Murray RG. Beneficial haemodynamic effects of intravenous dopexamine in patients with lowoutput heart failure. Journal of Cardiovascular Pharmacology 1987; 10: 280–6.

    Article  PubMed  CAS  Google Scholar 

  18. Dawson JR, Thomson DS, Signy M, Jvul SM, Turnbull P, Jenkins BS, Webb-Peploe MM. Acute haemodynamic and metabolic effects of dopexamine, a new dopaminergic receptor agonist, in patients with chronic heart failure. British Heart Journal 1985; 54: 313–20.

    Article  PubMed  CAS  Google Scholar 

  19. Svensson G, Sjögren A, Erhardt L. Short term haemodynamic effects of dopexamine in patients with chronic heart failure. European Heart Journal 1986; 7(8): 697–703.

    PubMed  CAS  Google Scholar 

  20. Colvin JR, Kenny GNC. Development and evaluation of a dual-pump microcomputer-based closed loop arterial pressure control system. International Journal of Clinical Monitoring and Computing, 1989; 6: 31–5.

    Article  PubMed  CAS  Google Scholar 

  21. Colvin JR, Kenny GNC. Automatic Control of arterial pressure after cardiac surgery: Evaluation of a microcomputer-based control system using glyceryl trinitrate and sodium nitroprusside. In press.

  22. Chaudhri S, Kenny GNC. The nitroprusside sparing effect of enoximone. In press.

  23. Sheppard LC, Shotts JF, Robertson NF, Wallace FD, Kouchoukos NT. Computer controlled infusion of vasoactive drugs in post-cardiac surgical patients. The New York State Society of Anesthesiologists Inc. 35th Postgraduate Assembly 1981, Dec 12–16.

  24. De Asla RA, Benis AM, Jurado RA, Litwak RS. Management of postcardiotomy hypertension by microcomputer controlled administration of sodium nitroprusside. Journal of Thoracic and Cardiovascular Surgery 1985; 89: 115–20.

    PubMed  Google Scholar 

  25. Reid JA, Kenny GNC. Evaluation of closed loop control of arterial pressure after cardiopulmonary bypass. British Journal of Anaesthesia 1987; 59: 247–55.

    Article  PubMed  CAS  Google Scholar 

  26. Hodsman NBA, Colvin JR, Kenny GNC. The effect of ketanserin on sodium nitroprusside requirements, blood pressure control and heart rate following coronary artery bypass surgery. British Journal of Anaesthesia. In press.

  27. Gollub SB, Emmot WW, Johnson DE, Sights KA, Wilson DB, Vacek JL, Hassanein K. Haemodynamic effects of dopexamine hydrochloride infusions of 48 to 72 hours duration for severe congestive heart failure. American Journal of Cardiology 1988; 62: 83C-88C.

    Article  PubMed  CAS  Google Scholar 

  28. Van der Starre PJA, Rosseel PMJ. Dopexamine hydrochloride after coronary artery bypass grafting. American Journal of Cardiology 1988; 62(5): 78C-82C.

    Article  PubMed  Google Scholar 

  29. Van der Starre PJA, Scheijgrond HW, Reneman RS, Kolling JB. The use of ketanserin, a 5-OHT receptor antagonist for treatment of postoperative hypertension following coronary artery bypass surgery. Anaesthesia and Analgesia 1983; 62: 63–9.

    Google Scholar 

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Author notes

  1. John R. Colvin

    Present address: Division of Anaesthesia, Ninewells Hospital, DD1 95Y, Dundee, Scotland

Authors and Affiliations

  1. University Dept. of Anaesthesia, Glasgow Royal Infirmary, 8-16 Alexandra Parade, G31 2ER, Glasgow, Scotland

    John R. Colvin, Sofia Chaudhri & Gavin N. C. Kenny

Authors
  1. John R. Colvin
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  2. Sofia Chaudhri
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  3. Gavin N. C. Kenny
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Colvin, J.R., Chaudhri, S. & Kenny, G.N.C. Evaluation of dopexamine hydrochloride as an anti-hypertensive agent after cardiac surgery. J Clin Monit Comput 8, 95–100 (1991). https://doi.org/10.1007/BF02915542

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  • DOI: https://doi.org/10.1007/BF02915542

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