Abstract
In a rare case of bronchogenic cyst with high carbohydrate antigen (CA) 19-9 production, a 57-year-old man with coughing and chest pain was diagnosed with a subcarinal mediastinal tumor. Fiberoptic bronchoscopy showed an erosive mucosal lesion overlying the area of extrinsic compression at the membranous of the right mainstem bronchus. Serum carbohydrate antigen 19-9 was elevated at 1300 U/ml. Thoracotomy showed an encapsulated cyst tightly adhering to the right main bronchus. The cyst was extirpated after ablation at the adherent cystic wall by electrocautery. Although intracystic carbohydrate antigen 19-9 concentration was very high, serum carbohydrate antigen 19-9 and bronchoscopic findings returned to normal postoperatively. The histological diagnosis was consistent with a bronchogenic cyst and carbohydrate antigen 19-9 could be immunohistochemically demonstrated within its epithelium.
Similar content being viewed by others
References
Uyama T, Monden Y, Sumitomo M, Miura K, Kimura S. CEA and CA 19-9 in benign pulmonary or mediastinal cystic lesions. J Surg Oncol 1989, 41: 103–8.
Okubo A, Sone S, Ogushi F, Ogura T, Uyama T, Monden Y, et al. A case of bronchogenic cyst with high production of antigen CA 19-9. Cancer 1989; 63: 1994–7.
Nakamura A, Uchiyama Y, Yamaoka N, Ide S, Yamashita H. A resected case of bronchogenic cyst of the left hemidiaphragm with elevated serum CA 19-9 (Eng abstr). J Jpn Assn Thorac Surg 1997; 45: 79–83.
Sumi Y, Ohno K, Yamasaki Y, Hatanaka N, Yamamoto S. Mediastinal bronchogenic cyst associated with high serum level of CA 19-9. A surgical case report. Jpn J Thorac Cardiovasc Surg 1998; 46: 110–4.
St-Georges R, Deslauriers J, Duranceau A, Vaillancourt R, Deschamps C, Beauchamp G, et al. Clinical spectrum of bronchogenic cysts of the mediastinum and lung in the adult. Ann Thorac Surg 1991; 52: 6–13.
Patel SR, Meeker DP, Biscotti CV, Kirby TJ, Rice TW. Presentation and management of bronchogenic cysts in the adult. Chest 1994; 106: 79–85.
Wychulis AR, Payne WS, Clagett OT, Woolner LB Surgical treatment of mediastinal tumors. J Thorac Cardiovasc Surg 1971; 62: 379–92.
Suen HC, Mathisen DJ, Grillo HC, LeBlanc J, McLoud TC, Moncure AC, et al. Surgical management and radiological characteristics of bronchogenic cysts. Ann Thorac Surg 1993; 55: 476–81
Martinod E, Pons F, Azorin J, Mouroux J, Dahan M, Faillon JM, et al. Thoracoscopic excision of mediastinal bronchogenic cysts: results in 20 cases. Ann Thorac Surg 2000; 69: 1525–8.
Read CA, Moront M, Carangelo R, Holt RW, Richardson M. Recurrent bronchogenic cyst. An argument for complete surgical excision. Arch Surg 1991; 126: 1306–8.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Okabayashi, K., Motohiro, A., Ueda, H. et al. Subcarinal bronchogenic cyst with high carbohydrate antigen 19-9 production. Jpn J Thorac Cardiovasc Surg 50, 46–48 (2002). https://doi.org/10.1007/BF02913488
Received:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/BF02913488