Abstract
Marked periosteal hyperostotic bone changes were found in a one year 4 month old girl with copper deficiency during long-term total parenteral nutrition after massive small bowel excision. She had difficultly to move her extremities because of pain. Laboratory examinations revealed amenia, neutropenia and extremely low level of the serum copper (2 μg/dl). Two weeks after copper administration, the serum copper level became normal and she resumed active motions. Radiographic findings were almost normal 7 months after copper treatment.
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Iyoda, K., Tsuda, M. & Nogami, H. Periosteal hyperostosis associated with copper deficiency-report of a case. JBMM 7, 42–45 (1989). https://doi.org/10.1007/BF02911533
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DOI: https://doi.org/10.1007/BF02911533