Skip to main content

Differential diagnosis of hepatitis and liver cirrhosis by means of cholecystography


19 patients suffering from acute or subacute hepatitis and 19 cases of liver cirrhosis were subjected to cholecystography with dye given per os in the usual manner, at a time when the icterus index was below 1:30. The shadow of the gallbladder appeared normal in 15 cases of hepatitis, was less pronounced than normal in 3 cases, and in one case in which the patient suffered also from cholelithiasis, it did not appear at all. In the cases of liver cirrhosis, the shadow of the gallbladder did not appear normal in any of the cases; in 6 of the cases a slight shadow was observable, and in 13 cases, no shadow could be observed. A comparison with some hepatic function tests also suggested that cholecystography may be of some help in the differential diagnosis of hepatitis and liver cirrhosis.

This is a preview of subscription content, access via your institution.


  1. 1.

    Graham, E. A., und Cole, W. H.: Roentgenologic examination of the gall-bladder; preliminary report of a new method utilizing the injection of tetrabromphenol-phthalein, J.A.M.A. 82:613(Feb.) 1924.

    Google Scholar 

  2. 2.

    Graham, E. A., Cole, W. H., and Cooper, G. H.: Visualization of the gallbladder by the sodium salt of tetra-bromphenolphthalein, J. A. M. A. 82:1777 (May) 1924.

    Google Scholar 

  3. 3.

    Rowntree, L. G., Hurwitz, S. H., and Bloomfield, A. L.: An experimental and clinical study of the value of phenol-tetrachlorphthalein as a test of hepatic function, Bull. Johns Hopkins Hosp. 24:327, 1913.

    Google Scholar 

  4. 4.

    Blomström, H. L., and Sandström, C.: On cholceystography in cases of impaired liver function, Acta chir. Scand. 71:135, 1932.

    Google Scholar 

  5. 5.

    Bockus, H. L.: Gastro-enterology, volume III, Phila-delphia and London, W. B. Saunders Co., 1946, p. 492.

    Google Scholar 

  6. 6.

    Lichtman, S. S.: Diseases of the liver, gallbladder and bile ducts, Second edition, Philadelphia, Lea & Febiger, 1949, p. 232.

    Google Scholar 

  7. 7.

    Nord, F.: La cholécystographie dans l’Hépatite Aiguë, Acta med. Scand. 75:205, 1931.

    Google Scholar 

  8. 8.

    Jacobi, H. G.: Glucose tolerance as diagnostic aid in jaundice: toxic hepatitis, Am. J. Digest. Dis. & Nutrition. 4:162 (May) 1937.

    Google Scholar 

  9. 9.

    Lindqvist, T., and Sohrne, G.: X-ray investigation of the gallbladder in pernicious anemia, Acta med. Scan. 116:117, 1944.

    Google Scholar 

  10. 10.

    Beaver, D. C., and Pemberton, J. de J.: Pathologic anatomy of liver in exophthalmic goiter, Ann. Int. Med. 7: 687 (Dec.) 1933.

    Google Scholar 

  11. 11.

    Foss, H. L.: Hunt, H. F., and McMillan, R. M.: The pathogenesis of crisis and death in hyperthyroidism, J. A. M. A. 113:1090 (Sept.) 1939.

    Google Scholar 

  12. 12.

    Krusius, F-E., The clinical significance of some lability reactions, Ann. Med. Int. Fenn. 39:192, 1950.

    PubMed  CAS  Google Scholar 

Download references

Author information



Corresponding authors

Correspondence to Klaus A. J. Järvinen or Vilho E. Paltia.

Rights and permissions

Reprints and Permissions

About this article

Cite this article

Järvinen, K.A.J., Paltia, V.E. Differential diagnosis of hepatitis and liver cirrhosis by means of cholecystography. Amer. Jour. Dig. Dis. 19, 244–248 (1952).

Download citation


  • Hepatitis
  • Bile Duct
  • Liver Cirrhosis
  • Liver Function Test
  • Cholelithiasis