Summary
Examination for lung asbestos bodies and pleural plaques was made in 996 consecutive unselected autopsies in Torino. The prevalence of asbestos bodies was 12.4% and that of pleural plaques 19.1%. Both findings were found with significantly greater frequency in men, and in the age group above 50 years. In addition, their occurrence increased with age up to 70 years, then decreased thereafter. A significant association between the severity of plaque lesions and the presence of asbestos bodies was found, whereas the number of asbestos bodies was not related to the presence of pleural plaques. It is suggested that pleural plaques are more reliable markers of asbestos exposure started many years earlier, and that lung asbestos bodies are more reliable indicators of more recent exposure.
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Andrion A., Bordone C., Bassi A., Bassi N., Scarfò A.: Sulla morfologia delle placche pleuriche — Morgagni (Milano)12 (Suppl.), 21, 1979.
Andrion A., Bertasso L., Bordone C., Colombo A., Dacorsi M., Mollo F.: Sulla ricerca dei corpuscoli dell’asbesto nel polmone, in preparati per sezione e per striscio: osservazioni comparative — Morgagni (Milano)13, 31, 1980.
Andrion A., Colombo A., Dacorsi M., Mollo F.: Pleural plaques at autopsy in Turin. A study on 1,019 adult subjects — Europ. J. resp. Dis.63, 107, 1982.
Andrion A., Pira E., Fadda T., Mollo F.: Lung asbestos bodies and pulmonary cancer in subjects without occupational exposure — Tumori. (Submitted for publication).
Arul K. J., Holt P. F.: Clearance of asbestos bodies from the lung: a personal view — Brit. J. industr. Med.37, 273, 1980.
Becklake M. R.: Asbestos-related diseases of the lung and other organs: their epidemiology and implications for clinical practice — Amer. Rev. resp. Dis.114, 187, 1976.
Bertasso L., Dacorsi M., Andrion A., Mollo F.: Sulla ricerca dei corpuscoli dell’asbesto nel polmone, in preparati per striscio: nota di tecnica — Morgagni (Milano)11 (Suppl.), 1, 1978.
Bianchi C., Brollo A., Miniussi C., Bittesini L.: Asbestos exposure in the Monfalcone area. A social and pathological study of 100 autopsy cases — Tumori67, 279, 1981.
Botham S. K., Holt P. F.: The mechanism of formation of asbestos bodies — J. Path. Bact.96, 443, 1968.
Botham S. K., Holt P. F.: Development of asbestos bodies on amosite, chrysotile and crocidolite fibers in guinea-pig lungs — J. Path. Bact.105, 159, 1971.
Churg A., Warnock M. L.: Asbestos and other ferruginous bodies. Their formation and clinical significance — Amer. J. Path.102, 447, 1981.
Churg A., Warnock M. L., Green N.: Analysis of the cores of ferruginous (asbestos) bodies from the general population. II. True asbestos bodies and pseudoasbestos bodies — Lab. Invest.40, 31, 1979.
Colombo A., Andrion A., Bertasso L., Mollo F.: Frequenza di placche pleuriche ialine in una casistica di 862 autopsie a Torino — Morgagni (Milano)12 (Suppl.), 17, 1979.
Doniach J., Swettenham K. V., Hathorn M. K. S.: Prevalence of asbestos bodies in a necropsy series in East London: association with disease, occupation and domiciliary address — Brit. J. industr. Med.32, 16, 1975.
Donna A.: Corpuscoli dell’asbestosi nel polmone umano reperiti nel comune materiale autoptico. In: Atti del Convegno di Studi sulla Patologia da Asbesto. Provincia di Torino Ed., 1968; p. 49.
Ghezzi I., Molteni G., Puccetti U.: Asbestos bodies in the lungs of inhabitants of Milan — Med. Lavoro58, 223, 1967.
Gross P., Cralley L. J., De Treville R. T. P.: ‘Asbestos’ bodies: their nonspecificity — Amer. industr. Hyg. Ass. J.28, 541, 1967.
Hillerdal G.: Pleural plaques. Occurrence, exposure to asbestos, and clinical importance — Acta Univ. upsal. 1980; vol. 363.
Luton P., Champeix J., Faure P.: The significance of the presence of the asbestos body in the expectoration of workers in asbestos — Arch. Mal. prof.8, 56, 1947.
Meurman L.: Asbestos bodies and pleural plaques in a Finnish series of autopsy cases — Acta path. microbiol. scand.181 (Suppl.), 1, 1966.
Mollo F., Andrion A., Bertasso L., Colombo A.: Placche pleuriche ialine ed esposizione all’asbesto — Pathologica72, 55, 1980.
Mollo F., Andrion A., Colombo A., Comino A., Dacorsi M., Passarino G.: Il riscontro autoptico per la conoscenza di broncopatie e pneumoconiosi — Recenti Progr. Med.71, 463, 1981.
Peacock P. R., Biancifiori C., Bucciarelli E.: Examination of lung smears for asbestos bodies in 109 consecutive necropsies in Perugia — Europ. J. Cancer5, 155, 1969.
Rubino G. F., Scansetti G., Pira E., Piolatto G., Mollo F., Andrion A., Colombo A., Bertasso L.: Pleural plaques and lung asbestos bodies in the general population. An autoptical and clinical-radiological survey. In:Wagner J. C. (Ed.): Biological effects of mineral fibres. Proc. IARC Symp., Lyon, 1979. IARC Sci. Publ., 1980; p. 545.
Selikoff I. J., Lee D. H. K.: Asbestos and disease — Academic Press, New York, 1978.
Whitwell F.: Problems in the pathology of disease caused by asbestos — J. roy. Soc. Med.71, 919, 1978.
Zielhuis R. L.: Public health risks of exposure to asbestos — Pergamon Press, Oxford, 1977; p. 73.
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Andrion, A., Colombo, A. & Mollo, F. Lung asbestos bodies and pleural plaques at autopsy. La Ricerca Clin. Lab. 12, 461–468 (1982). https://doi.org/10.1007/BF02909397
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DOI: https://doi.org/10.1007/BF02909397