Summary
T lymphocyte subpopulations defined by monoclonal antibodies were determined in patients with essential mixed cryoglobulinemia (EMC) and secondary cryoglobulinemias (SC). A decrease of circulating lymphocytes and a reduction in the absolute number of T3+, T4+ and T8+ (p<0.01) as well as in the percentage of T4+ lymphocytes (p<0.05) were found in EMC. A significant decrease of T8+ cells, both in percentage (p<0.01) and absolute number (p<0.001), was evidenced in SC, while T3+ and T4+ cell counts were not significantly different from those of healthy controls.
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Galli, M., Monti, G., Irato, L. et al. T lymphocyte subpopulations defined by monoclonal antibodies in essential mixed cryoglobulinemia and in secondary cryoglobulinemias. La Ricerca Clin. Lab. 16, 275–279 (1986). https://doi.org/10.1007/BF02909350
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DOI: https://doi.org/10.1007/BF02909350