Summary
The ultrastructure of 5 griseofulvin-resistant fungi of favus was studied by image processing with microcomputer. It was found that the cell walls of the fungi consisted of 8 layers, and the inner layer containing cytoplasm was loose. It was also found that all structures within the cytoplasm possessed a 1–3 layers integral envelope with chromatins in the nucleus. These might be contributing factors in the development of resistance to gri eofulvin. This multiple-layered, thick cell wall might act as a barrier responsible for the impermeability of the cell to gritseofulvin.
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References
1984;64:657–9.
Werner HJ, et al. Electron microscope observations on the fine structuve of Microsporum canis. J Invest Derm 1966; 46:130–4.
Werner HJ, et al. Electron microscopic observations of Epidermophyton flocco-sum. J Invest Derm 1964;43:139–43.
Kitajima Y, et al. Fine architecture of cell walls in pathogenic fungi. JPN J Med Mycol 1984;25:94–101.
1986;15:58.
1980;249-62.
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Yue-chen, Z., Zhao-ru, Z., Pei-jin, L. et al. Image processing by microcomputer on ultrastructure of griseofulvin-resistant fungi in favus. Journal of Tongji Medical University 10, 60–64 (1990). https://doi.org/10.1007/BF02909125
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DOI: https://doi.org/10.1007/BF02909125