Summary
Karyotypes and in vitro cultures of bone marrow cells from eleven patients with acute myelogenous leukemia M2 type were performed. 8/21 translocation was found in 5 patients. In all of them the cultures in vitro shared one characteristic, i.e., clusters were small and less in number. These patients could relatively easily obtain complete remission. The similarity of CFU-GM in patients with t (8;2l) may be another important biological phenotype.
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Guo-xian, S., Bian-ming, W., Ai-de, Y. et al. Characteristic of marrow culture and clinical relevance in leukemia with 8/21 translocation. Journal of Tongji Medical University 9, 228–231 (1989). https://doi.org/10.1007/BF02909088
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DOI: https://doi.org/10.1007/BF02909088