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The electrogram from sinus venosus of toad recorded in vitro and the effect of high concentration of potassium and calcium on it

Das Elektrosinogramm des isolierten Sinus venosus der Kröte und die Beeinflussung desselben durch Hyperkalie und Hyperkalzie

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Summary

Using direct extracellular lead the electrical activity of toad’s sinus venosus may he recorded by electrocardiograph. Ordinarily two waves could be recorded in each cycle and were named wave N and wave P respectively. Intracellular recording indicates that wave N reflects the electrical activity of the pacemaker cells while wave P reflects that of the working cells situated in sinus venosus or atrial cells.

We have observed the effect of high potassium, high potassium plus calcium on the activity of sinus venosus. The results indicate that high potassium evokes intrasinal or sinoatrial block and thus slows the cardiac rhythm which can be antagonized by high calcium

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References

  1. Surawicz B: Relationship between electrocardiogram and electrolyte. Am Heart J. 73:814, 1967

    Article  PubMed  CAS  Google Scholar 

  2. Strauss HC, et al: Electrophysiological properties of the rabbit sinoatrial perinodal fibers. Circ Res 31:490, 1972

    PubMed  CAS  Google Scholar 

  3. Irisawa H: Comparative physiology of the cardiac pacemaker mechanism. Physiol Rev 58(2):461, 1978

    PubMed  CAS  Google Scholar 

  4. Masson-Pevet M, et al: Sinus node and atrium cells from the rabbit heart: A quantitative electron microscopic description after electrophysiological localization. J Mol Cell Cardiol 11:555, 1979

    Article  PubMed  CAS  Google Scholar 

  5. Cramer M, et al: Characteristics of extracellular potentials recorded from the sinoatrial pacemaker of the rabbit. Circ Res 41:292, 1977

    PubMed  CAS  Google Scholar 

  6. Cramer M, et al: Electrograms from the canine sinoatrial pacemaker recorded in vitro and in situ. Am J Cardiol 42:939, 1978

    Article  PubMed  CAS  Google Scholar 

  7. Hoffman BF, et al: Electrophysiology of the heart, pp l20–121, McGraw Hill Book Co, New York, 1960

    Google Scholar 

  8. Vassalle M 45, 1978

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Authors and Affiliations

  1. Department of Physiology, Wuhan Medical College, Wuhan

    Yang Lie Postgraduate & Li Shaoru

Authors
  1. Yang Lie Postgraduate
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  2. Li Shaoru
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Lie, Y., Shaoru, L. The electrogram from sinus venosus of toad recorded in vitro and the effect of high concentration of potassium and calcium on it. Acta Academiae Medicinae Wuhan 2, 82–86 (1982). https://doi.org/10.1007/BF02908870

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  • DOI: https://doi.org/10.1007/BF02908870

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