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Antimicrobial effects of new 1-(1,2,4-triazol-1-yl)-acetanilides

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Abstract

Fourteen synthetically prepared 1-(1,2,4-triazol-1-yl)acetanilides were tested for antimicrobial effect. None of the prepared derivatives influenced theB. subtilis, P. fluorescens nor the tested yeasts. Only the derivatives with substituents in positionspara orortho andpara were biologically effective. The widest antimicrobial spectrum was manifested by the pentachloro derivative, which was effective with G+ and G− bacteria and with filamentous fungi.

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Authors and Affiliations

  1. Department of Microbiology, Biochemistry and Biology, Slovak Technical University, 812 37, Bratislava, Slovakia

    S. Jantová & D. Hudecová

  2. Department of Organic Chemistry, Faculty of Chemical Technology, Slovak Technical University, 812 37, Bratislava, Slovakia

    Š. Stankovský & K. Špirková

Authors
  1. S. Jantová
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  2. D. Hudecová
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  3. Š. Stankovský
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  4. K. Špirková
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Jantová, S., Hudecová, D., Stankovský, Š. et al. Antimicrobial effects of new 1-(1,2,4-triazol-1-yl)-acetanilides. Folia Microbiol 39, 152–154 (1994). https://doi.org/10.1007/BF02906812

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  • DOI: https://doi.org/10.1007/BF02906812

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