Summary
Erythrocyte membrane glycoproteins undergo various types of modification during the life of the cell in the circulation; when only sialic acid is removed, the younger red cells can be repaired in the liver and return to the circulation. Otherwise, when an autolytic mechanism removing a sialopeptide becomes active as a consequence of the metubolic impairment of the cell, the erythrocyte is probably trapped by the hemocatheretic organs and destroyed.
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This work was supported by grants from theConsiglio Nazionale delle Ricerche (CNR), Roma, Italy
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Balduini, C., Brovelli, A., Balduini, C.L. et al. Structural modifications in membrane glycoproteins during the erythrocyte life-span. La Ricerca Clin. Lab. 9, 13–22 (1979). https://doi.org/10.1007/BF02905023
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DOI: https://doi.org/10.1007/BF02905023