Abstract
Twenty three kojic acid derivatives were tested in the agar diffusion test against twenty five dermatophytic fungi. The inhibitory effects at equal doses (10 mg/L) were correlated with the 1-octanol — water partition coefficients of the compounds. An improvement in antifungal activity can be achieved by increasing the hydrophobicity of the compounds.
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This work was supported by Slovak Grant Agency (grant no. 1/4404b4/42).
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Baláž, Š., Uher, M., Brtko, J. et al. Relationship between antifungal activity and hydrophobicity of kojic acid derivatives. Folia Microbiol 38, 387–391 (1993). https://doi.org/10.1007/BF02898762
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DOI: https://doi.org/10.1007/BF02898762