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The effect of serum carotenoids on atrophic gastritis among the inhabitants of a rural area in Hokkaido, Japan

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Environmental Health and Preventive Medicine Aims and scope

Abstract

A total of 206 residents (76 males and 130 females) of a rural area of Hokkaido, Japan, attending a health check in August, 1997, were studied to assess the relationship between serum carotenoids and atrophic gastritis (AG). Of the participants, 91 had AG as indicated by their serum levels of pepsinogen I and pepsinogen II. Logistic regression analysis, after adjusting for gender and age, revealed that the odds ratios for serum carotenoid levels were lower for subjects with high serum levels of α-carotene (odds ratio, 0.41; 95% C.I., 0.19–0.88) and β-carotene (odds ratio, 0.41; 95% C.I., 0.18–0.91) than for those with low serum carotenoid levels. In addition, the odds ratios of subjects with high serum levels of β-cryptoxanthin (odds ratio, 0.60; 95% C.I., 0.28–1.31), provitamin A (odds ratio, 0.38; 95% C.I., 0.17–0.85), and retinol (odds ratio, 0.67; 95% C.I., 0.31–1.48) were found to be lower than the odds ratios for those with low serum levels. Odds ratios for subjects with high serum zeaxanthin/lutein levels were higher than odds ratios for those with low serum levels. These results suggest that frequent intake of foods ric, in carotenoids with provitamin A activity may reduce the risk of AG.

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Authors and Affiliations

  1. Department of Public Health, Fujita Health University School of Health Sciences, Dengakugakubo, Kutsukake-cho, 470-1192, Toyoake City, Aichi Prefecture, Japan

    Yoshinori Ito & Koji Suzuki

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  1. Yoshinori Ito
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  2. Koji Suzuki
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Correspondence to Yoshinori Ito.

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Ito, Y., Suzuki, K. The effect of serum carotenoids on atrophic gastritis among the inhabitants of a rural area in Hokkaido, Japan. Environ Health Prev Med 6, 184–188 (2001). https://doi.org/10.1007/BF02897968

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  • DOI: https://doi.org/10.1007/BF02897968

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