Abstract
The purpose of this study was to investigate the effect of weight reduction on the anti-mutagenicity of human saliva. Subjects were 16 male college judo players. The anti-mutagenicity of the saliva was measured using the umu test. There was an inhibiting effect of the saliva on the mutagenicity of AF-2. However, a modifying effect of the saliva on Trp-P-1 was not observed. On the day before a competition and 7 days after the competition, the inhibiting capacity of the saliva for the mutagenicity of AF-2 decreased and increased in two non-weight reduction and two weight reduction groups, respectively.
However, on the day before the competition, the changed body weights (r=−0.77, p<0.01) and BMI (r=−0.77, p<0.01) were significantly correlated with that of the inhibiting capacity of the saliva for the mutagenicity of AF-2. In addition, the BMI at 20 days before the competition was not significantly but markedly correlated with it (r=0.50, p=0.057). At 7 days after the competition, however, these correlations were not found.
These findings suggest a unique correlation between the anti-mutagenicity of human saliva and body weight or BMI.
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Toda, M., Morimoto, K., Nakamura, Si. et al. The unique correlation between anti-mutagenicity of human saliva and change in body weight. Environ Health Prev Med 6, 82–87 (2001). https://doi.org/10.1007/BF02897950
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DOI: https://doi.org/10.1007/BF02897950