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Production of rhodomycins inStreptomyces griseoruber 4620

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Abstract

The strainStreptomyces griseoruber 4620 produces, besides the anthracycline antibiotics beromycins, some other anthracyclines of the rhodomycin type. Twelve isolates exhibiting a higher antibiotic activity (up to 2.5×), as compared to the parent strain, were obtained after a spontaneous selection. The following species were isolated from the hydrolysate of mycelial extract: β-rhodomycinone, β-isorhodomycinone, α2-rhodomycinone and 10-deoxy-β-rhodomycinone, which has not yet been described.

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Authors and Affiliations

  1. Department of Molecular Biology and Genetics, Institute of Microbiology, Czechoslovak Academy of Sciences, 142 20, Prague 4

    M. Podojil, M. Blumauerová, V. Přikrylová & Z. Vaněk

  2. Institute of New Antibiotics, Academy of Medical Sciences of the USSR, Moscow

    G. F. Gauze & T. S. Maksimova

Authors
  1. M. Podojil
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  2. M. Blumauerová
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  3. V. Přikrylová
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  4. Z. Vaněk
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  5. G. F. Gauze
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  6. T. S. Maksimova
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Podojil, M., Blumauerová, M., Přikrylová, V. et al. Production of rhodomycins inStreptomyces griseoruber 4620. Folia Microbiol 25, 464–466 (1980). https://doi.org/10.1007/BF02897211

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  • DOI: https://doi.org/10.1007/BF02897211

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