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Immunocytochemical study of S-100 protein in human pituitary adenomas

Virchows Archiv B volume 55, pages 107–109 (1988)Cite this article

Summary

The S-100 protein was localized by immunocytochemistry in 70 pituitary tumors including 30 prolactin, 16 growth hormone, two corticotropin and 22 non-functioning adenomas. Positive immunostaining was observed in only one case (prolactin adenoma). It is concluded that in functioning and non-functioning pituitary tumors there is no particular involvement of S-100 protein-containing cells, at least under the conditions of this study.

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Author information

Affiliations

  1. Department of Endocrinology, Hôpital de la Pitié, 83 Bd. de l’Hôpital, F-75013, Paris

    Gérard Turpin & Hassan M. Heshmati

  2. Department of Histology, CHU Pitié Salpêtrière, F-75013, Paris, France

    Michèle Kujas, Jean Grémain & Jean Racadot

  3. Department of Neurochemistry, CHU Pitié Salpêtrière, F-75013, Paris, France

    Claude M. Jacque

Authors
  1. Gérard Turpin
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  2. Hassan M. Heshmati
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  3. Michèle Kujas
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  4. Jean Grémain
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  5. Claude M. Jacque
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  6. Jean Racadot
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Turpin, G., Heshmati, H.M., Kujas, M. et al. Immunocytochemical study of S-100 protein in human pituitary adenomas. Virchows Archiv B Cell Pathol 55, 107–109 (1988). https://doi.org/10.1007/BF02896566

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  • DOI: https://doi.org/10.1007/BF02896566

Key words

  • S-100 protein
  • Human pituitary adenomas
  • Immunocytochemistry