Summary
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1.
In a series of 37 pédiatrie patients with bowel dysfunction, including constipation, diarrhea, and irritable bowel syndrome, methylcellulose was a helpful adjunct to general management.
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2.
A good response was obtained in 34 of the 37 cases and in most instances, it was possible to discontinue medication after a reasonable period without recurrence.
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3.
Patients with pseudomegacolon, who had previously obtained poor results with antispasmodics, were benefited by methylcellulose.
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4.
Although 17 children in the series had allergic manifestations, no allergic symptoms due to methylcellulose (Cellothyl) developed in any of the patients during treatment. On the contrary, in 2 children with asthma and 2 with urticaria, the correction of their constipation was followed by relief of the allergy.
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References
Boekus, H. L.: Gastroenterology, Vol. II, W. B. Saunders, Philadelphia, Pa., 1943. Pages 510–511.
Mitchell-Nelson: Textbook of Pediatrics, W. B. Saunders, Philadelphia, Pa., 5th Ed. 1950. Page 808.
Editorial, J. A. M. A. 127:922 (Apr. 14) 1945.
Schweig, Karl: The Use of Methylcellulose as a Bulk Laxative; New York State J. of Med. 48:1822–1823 (Aug. 15) 1948.
Bargen, J. A.: A Method of Improving Function of the Bowel: The Use of Methylcellulose; Gastroenterology 13: 275 (Oct.) 1949.
Goetzel, Franz R. and Newey, James A.: Methyl Cellulose Therapy in Chronic Constipation; Permanente Found. M. Bull. 7:67–78 (July) 1949.
Musiek, Vern. II.: Effectiveness of Methyleellulose in Gastrointestinal Disturbances: J. Oklahoma M. A. 43:360–364, (August) 1950.
Hirschman, L. J.: Some Common Proctologic Conditions of Childhood; J. South Carolina M. A. 42:267–272 (Oct.) 1946.
Gelfand, H. Harold: The Vegetable Gums by Ingestion in the Etiology of Allergic Disorders; J. Allergy 20:311–321 (Sept.) 1949.
Feinberg, Samuel A. and Schoenkerman, Bert B.: Karaya and Related Gums as Causes of Atopy; Wisconsin M. J. 39:734–736, 1940.
Best, Charles H. and Taylor, Norman B.: The Physiological Basis of Medical Practice; The Williams & Wilkins Company, Baltimore, Maryland, 4th Ed. 1945. Page 504, 508.
Sollmann, T.: Manual of Pharmacology, W. B. Sanders Co., Philadelphia, Pa., 7th Ed. Page 26.
Seidmon, E. E. P., and Arnold, L.: Influence of Vitamin A and B Deficiency upon Intestinal Acid-base Equilibrium and Bacterial Flora; Proc. Soc. Exp. Biol. and Med. 29: 158–490, 1932.
Alvarez, Walter C.: An Introduction to Gastroenterology, Paul B. Hoeber Inc., New York, 3rd Impression, 1939. Page 553.
Shugar, M. and Arnold, L.: Absorption of Bacteria from the Large Intestine: Proc. Soc Exp. Biol. and Med. 29:494–496, 1932.
Fisher, V.: Absorption of Yeast from the Large Intestine: Proc. Soc. Exp. Biol. and Med. 29:490–494, 1932.
Schweinburg, F. B., Seliginan, A. M. and Fine, J.: Transmural Migration of Intestinal Bacteria; New England J. Med. 242:747–751 (May 11) 1950.
Gray, I., and Walzer, M.: Studies in Absorption of Undigested Protein in Human Beings. VIII Absorption from the Rectum and a Comparative Study of Absorption Following Oral, Duodenal and Rectal Administration; J. Allergy 11:245–250, 1940.
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Seidmon, E.P. Management of bowel dysfunctions in children. Amer. Jour. Dig. Dis. 18, 274–278 (1951). https://doi.org/10.1007/BF02896448
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DOI: https://doi.org/10.1007/BF02896448