Summary
-
1.
The literature of cardiac and gastro-intestinal relationships is reviewed and illustrative cases presented.
-
2.
The effect of reflex vagotonia on the coronary circulation is emphasized. Other methods of how the gastro-intestinal system may adversely affect the cardiovascular system are discussed.
-
3.
Gastro-intestinal disease may mimic cardiac disease.
-
4.
Correction of disease within the abdomen often serves to decrease cardiac load and improve circulatory function.
Similar content being viewed by others
References
Kuntz, Albert,The Autonomic Nervous System, 1934, Lea & Febiger.
White, J. C, Garrey, W. E., and Atkins, J. A., Cardiac Innervation: Experimental and Clinical Studies, Arch. Surg., 26:765, 1933.
Anrep, G. V., The Regulation of the Coronary Circulation, Physiological Rev., 6:596, 1926.
Wiggers, Am. J. Physiol. 24:391, 1909.
Morrison, L. M. and Swalm, W.A., Role of the Gastro-Intestinal Tract in Production of Cardiac Symptoms, J.A.M. A. 114:217, 1940.
Gilbert, N. C, Fenn, G. K., LeRoy, G. V., Effect of Distention of Abdominal Viscera on the Coronary Blood Flow and on Angina Pectoris, J. A. M. A. 215:1962, 1940.
Ravdin, I. S., Royster, H. P., Sanders, G. B., Reflexes Originating in the Common Duct giving rise to Pain Simulating Angina Pectoris, Ann. Surg. 115:1055, 1942.
Bellet, S., and Meade, R. H., Unpublished Observations.
Smith, F. M. and Miller, G. H., A Study of the Reflex In fluence of the Colon, Appendix and Gall Bladder on the Stomach, Am. J. Physiol. 90:518, 1929.
Hall, G. E., Ettinger, G. H., and Banting, F. G., An Experimental Production of Coronary Thrombosis and Myocardial Failure, Canad. M. A. J. 34:9, 1936.
Manning, G. AV., Hall, G. E., and Banting, F. G., Vagal Stimulation and the Production of Myocardial Damage, Canad. M. A. J. 37:314, 1937.
Babeock, R. H., Chronic Cholecystitis as a Cause of Myocardial Incompetence, J. A. M. A. 52:1904, 1909.
Straus, D. C. and Hamburger, W. W.,. The Significance of Cardiac Irregularities in Reference to the Operability of Cases of Cholelithiasis, Cholecystitis and Duodenal Ulcer, J. A. M. A. 82:706, 1924.
Ivy, A. C, Physiologic Disturbances Incident to Obstructive Jaundice, J. A. M. A. 95:1068, 1930.
Crittenden, P. J., and Ivy, A. C, A Study of Viscerocardiac Reflexes, Am. Heart J. 8:507, 1933.
Owens, S. E., A Study of Viscerocardiac Reflexes, Am. Heart J. 8:496, 1933.
Wakefield, H., The Association of Gall Bladder Disease with Heart Disease: Clinical and Experimental Observations, Med. Clin. N. A. 31:161 (Jan.) 1947.
Ray, B. S., and Stewart, H. J., Glossopharyngeal Neuralgia: A Cause of Cardiac Arrest, Am. Heart J. 35:458, 1948.
Weiss, S., and Ferris, E. B., Jr., Adams-Stokes Syndrome with Transient Complete Heart Block of Vago-vagal Reflex Origin, Arch. Int. Med. 54:931, 1934.
Wolferth, C. C, and Edeiken, J.: Differential Diagnosis of Angina Pectoris, with Special Reference to Esophageal Spasm and Coronary Occlusion, Penn. M. J. 45:579, 1942.
Jones, C. M., Hiatus Esophageal Hernia (Comparison of its Symptoms with those of Angina Pectoris), New Eng. J. Med. 225:963, 1941.
Olsen A. M. and Harrington, S. W., Esophageal Hiatal Hernias of the Short Esophagus Type: Etiologic and Therapeutic Considerations, J. Thoracic Surg. 17:189, 1948.
Gilbert, N. C, Recurrent Esophageal Hiatus Hernia, Med. Clin. N. A. 32:213, (Jan.) 1948.
Van Dellen, T. R., Personal Communication, 1949.
Vinson, P. P.,Diseases of the Esophagus, C. C. Thomas, 1940.
Iglauer, S. and Schwartz, B.A., Heart Block Periodically Induced by the Swallowing of Food in a Patient with Cardiospasm (Vago-vagal Syncope), Ann. Otol. Rhin, and Laryn. 45:875, 1936.
Rivers, A. B., “Peptic Ulcer,”Cyclopedia of Medicine,Surgery and Specialties, Vol. 14, p. 340, 1939, F. A. Davis Co., Philadelphia.
Levy, H., and Boas, E. P., Angina Pectoris and the Syndrome of Peptic Ulcer, Arch. Int. Med. 71:301, 1943.
Harrison, T. R., Clinical Aspects of Pain in the Chest. I, Angina Pectoris, Am. J. Med. Sci. 207:561, 1944.
Clark, N. E., Electrocardiographic Changes in Active Duodenal and Gall Bladder Disease, Am. Heart J. 29:628, 1945.
Mixter, W. J., Back Pain in Lesions of the Gastro-Intestinal Tract, with Particular Reference to Duodenal Ulcer, Am. J. Digest, Dis. and Nutrition 4:736, 1937.
Pardee, E. B., Cardiac Manifestations of Gastro-Intestinal Disease, Rev. Gastroenterology 16:395, 1949.
Harrison, T. R., Clinical Aspects of Pain in the Chest. Ill, Pain arising from the Stomach, Am. J. Med. Sci. 209:771, 1945.
Bockus, H. L.,Gastro-Enterology, W. B. Saunders, Phila., 1943, Vol. 1, p. 781.
Walters, W., Diverticula of the Stomach, J. A. M. A.131: 954, 1946.
Osier, W.,Practice of Medicine, Appleton-Century, 1901, p. 564.
Riesman, D., Development of Cardiac Murmurs during Attacks of Biliary Colic, J. A. M. A. 48:1589, 1907.
Mayo, William J., Certain Medical and Surgical Aspects of Disease of the Biliary Apparatus, Illinois Med. J. 45:33, 1924.
Willius, F. A. and Fitzpatrick, J. M., The Relationship of Chronic Infection of the Gall Bladder to Disease of the Cardiovascular System, J. Iowa State Med. Soc. 15:589, 1925.
Fitzhugh, T. Jr., and Wolferth, C. C, Cardiac Improvement following Gall Bladder Surgery, Ann. Surg. 10:478, 1935.
Weiss, M. M. and Hamilton, J. E., The Effect of Gall Bladder Disease on the Electrocardiogram, Surgery 6:893, 1939.
Breitweiser, E. R., Electrocardiographic Observations in Chronic Cholecystitis before and after Surgery, Am. J. Med. Sci. 213:598, 1947.
Engel, G. L. and Engel, F. L., The Significance of the Carotid Sinus Reflex in Biliary Tract Disease, New Eng. J. Med. 227:470, 1942.
Paxton, J. R. and Payne, J. H., Symptoms of Acute Pancreatitis, California Med. 67:241, 1947.
Gottesman, J., and Casten, D., Changes in the Electrocardiogram induced by Acute Pancreatitis, J. A. M. A. 123:892, 1943.
Gottesman, J., Casten, D., Beller, A. J., Electrocardiographic Changes Associated with Acute Pancreatitis, Proc. Soc. Exper. Biol. and Med. 49:365, 1942.
Bellet, S., quoted by Bockus, H. L.,Postgraduate Gastroenterology, W. B. Saunders, Phila., 1950, pp. 330–333.
Davis. H. A., Personal Communication, 1950.
Averbruck, S. H., Acute Generalized Peritonitis Simulating Coronary Artery Occlusion, J. Mt. Sinai Hosp., 8:335, 1942.
Steinberg, B., et al., Proc. Soc. Exper. Biol. and Med.30: 1155, 1933.
Fenn, G. K., Pain Simulating that of Coronary Disease, Med. Clin. N. A. 19:1077, 1936.
Levine, S. A. and Tranter, C, Infarction of the Heart Simulating Acute Surgical Abdominal Conditions, Am. J. Med. Sci. 155:57, 1918.
Yeagley, J. D., Cayer, D. and MacMillan, R. L., Gastrointestinal Symptoms in Coronary Heart Disease, N. Carolina Med. J. 10:22, 1949.
Schräger, V. L.. and Ivy, A. C, Symptoms Produced by Distention of the Gall Bladder and Biliary Duets, S. G. O. 47:1, 1928.
Brown, T. R., Cardiac Symptoms in Unsuspected Gall Bladder Disease,Libman Anniversary Volume I, 1932, p. 265.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Suckle, E., Wharton, G.K. The inter-relationship between cardiovascular function and gastro-intestinal disease. Amer. Jour. Dig. Dis. 18, 261–269 (1951). https://doi.org/10.1007/BF02896446
Received:
Issue Date:
DOI: https://doi.org/10.1007/BF02896446