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Adrenergic blocking agents: Their use in clinical medicine

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The American Journal of Digestive Diseases

Summary

In the past one has been able to affect the autonomic nervous system to a varying degree in most respects except in depression of the sympathetic or adrenergic nervous system ; but the latter is now becoming a reality in certain respects. The problem of applying adrenergic blockade has been attacked and encouraging results have been obtained so that the medical profession can now treat the varied syndrome of sympathetic predominance. Vasospastic conditions of the vascular tree, including neurogenic or essential hypertension, are peculiarly susceptible in many instances to adrenergic blockade, and it behooves the medical profession to become more aware of the role of sympatholytics and the newer suppressants of sympathetic overflow.

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References

  1. Berry. R. L.. Campbell. K. N.. Lvons. R. L., Moe. G. K. and Sutler. M. R.: The Use of Tetraethvlammouium in Peripheral Vascular Diseases and Causalgic Studies. Surgery, 20: 525, 1946.

    Google Scholar 

  2. Fellows. E. J., Macko. E., McLean, R. A., Kerwin, J. F., Hall. G.. Milnes, F. J. and Ullvot. G. E.: A Comparison of the Oral and Intravenous Adrenergic Blocking Activitv of a Number of Beta-bromo and Chloro-alkylamines. Jl. Pharm. & Exp. Ther. 101: 11. Jan. 1951.

    Google Scholar 

  3. Rothlin. E.: The Pharmacology of the Natural and Dihvdrogenated Alkaloids of Ergot. Bull. Acad. Suisse. Se. Med. 2: 1. 1946/47.

    Google Scholar 

  4. Grimson. K. S., Reardon, M. J. Marzoni, F. A. and Herrix. J. P.: The Effects of Priscol (2-benzyl-4. 5-imidazoliue HCI) on Peripheral Vascular Diseases. Hypertension and Circulation in Patients. Ann. Surg, 127: 968. 1948. Rogers, M. P.: Use of Sympatholvtie Dvuer (Priscol) from the Point of View a General Surgicnl Practitioner. J. A. M. A. 140: 272, May 21, 1949.

    Article  PubMed  CAS  Google Scholar 

  5. Meier, R.. Yonkman. F. F.. Carver. B. N. and Gross, F.: A New Imidazoline Derivative with Marked Adrenolvtic Properties. Proc. Soc. Exper. Biol. & Med. 71: 70, 1949.

    CAS  Google Scholar 

  6. Gross, F., Druey, J. and Meier. R.: A New Group of Depressor Substances with a Special Type of Effect. Experentia 6: 19, 1950. Freis, E. D. and Fiunerty, F. A., Jr.: Suppression of Vasomotor Reflexes in Man Following l-Hydrazinophthalazine (C-5968). Proc. Soc. Exper. Biol. and Med. 75: 23, Oct., 1950.

    Article  CAS  Google Scholar 

  7. Freis, E. D., Finnerty, Jr., F. A., and Walsh, W. B.: The Treatment of Severe Essential Hypertension. Medical Clinics of North America, 34: 1741, November, 1950. Yonkman, F. F., and Freis, E. D.: Rational Elimination of Side Reactions and/or Tolerance in the Development of Potentially Valuable Drugs. Aniology, 3:36, Feb. 1952.

    PubMed  CAS  Google Scholar 

  8. Schroeder, H. A.: Effects of Hypertension of Sulfhydryl and Hydrazine Compounds. Jl. Clin. Inves. June, 1951.

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Authors and Affiliations

  1. The Burrus Clinic, Inc., High Point, North Carolina

    Max P. Rogers

  2. Director of Research, Ciba Pharmaceutical Products, Inc., Summit, New Jersey

    Fredrick F. Yonkman

Authors
  1. Max P. Rogers
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  2. Fredrick F. Yonkman
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Rogers, M.P., Yonkman, F.F. Adrenergic blocking agents: Their use in clinical medicine. Amer. Jour. Dig. Dis. 19, 144–146 (1952). https://doi.org/10.1007/BF02893204

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  • DOI: https://doi.org/10.1007/BF02893204

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