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Effect of vitamin A supplementation on hematopoiesis in children with anemia

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Abstract

Fifty children (1–4 years age) presenting with microcytic hypochromic anemia (hemoglobin less than 10g/dl) were studied in two groups of 25 each. Group I was supplemented with iron (ferrous sulphate 6 mg/kg/d) while group II in addition to iron was also supplemented with vitamin A (5000 IU/d). Hemoglobin concentration was found to be significantly increased after 4 weeks of iron supplementation. Rise in hemoglobin was comparatively more in-group II, as compared to group I, after 8 and 12 weeks. Serum iron was significantly higher after 4 weeks in both the groups. Packed cell volume (PCV) and retinol levels increased significantly in-group II only. The data suggests that supplementation of vitamin A improves hematopoiesis.

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Authors and Affiliations

  1. Departments of Pediatrics, Pt. BD Sharma Post Graduate Institute of Medical Sciences, 124001, Rohtak, (Haryana)

    Arun Garg, Pankaj Abrol & AD Tewari

  2. Pathology, Pt. BD Sharma Post Graduate Institute of Medical Sciences, 124001, Rohtak, (Haryana)

    Rajiv Sen

  3. Biochemistry, Pt. BD Sharma Post Graduate Institute of Medical Sceinces, 124001, Rohtak, (Haryana)

    Harbans Lal

Authors
  1. Arun Garg
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  2. Pankaj Abrol
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  3. AD Tewari
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  4. Rajiv Sen
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  5. Harbans Lal
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Garg, A., Abrol, P., Tewari, A. et al. Effect of vitamin A supplementation on hematopoiesis in children with anemia. Indian J Clin Biochem 20, 85–86 (2005). https://doi.org/10.1007/BF02893048

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