Summary
Several analyses of the gastric juice of isolated stomach pouches are presented before and after oral administration of RD 11, a detergent complex. These analyses show a trend of inhibition of the secretion of total available pepsin, and lysozyme, but not much change in the acidity of the secretion. The viscosity increases in the post-medicated samples, as does the amount of mucin per sample. A humoral or/and nervous inhibition mechanism therefore seems to be concerned here.
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References
Fogelson, S. J., Lobstein, O. E.: Proc. Soc. Exp. Biol. & Med.,75: 334–337, 1950.
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Lobstein, O.E., Fogelson, S.J. The effect of detergent complex on the rate of secretion of gastric juice and its components in total pouches of the stomach. Amer. Jour. Dig. Dis. 18, 213–214 (1951). https://doi.org/10.1007/BF02891954
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DOI: https://doi.org/10.1007/BF02891954