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A cytophotometrical study on the centenarian hepatocyte

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Virchows Archiv B

Summary

Size alterations, both of cell and nucleus, of the centenarian hepatocyte followed a pattern proportionate to aging which was observed in the hepatocyte of non-centenarian groups and clearly followed nonagenarian in location on the graph. When size alterations of the hepatocyte were considered as an aging parameter, the present observation suggests that the centenarian could be a group next to the nonagenarian. The results obtained by present cytomorphometrical analysis do not favor a hypothesis that the centenarian is a select population in terms of longevity.

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Authors and Affiliations

  1. Department of Medicine, Tokyo Metropolitan Geriatric Hospital, 35-2, Sakae-cho, 173, Itabashi-ku, Tokyo, Japan

    Toshimitsu Watanabe

  2. Department of Pathology, Tokyo Metropolitan Institute of Gerontology, 35-2, Sakae-cho, 173, Itabashi-ku, Tokyo, Japan

    Yasukazu Tanaka

  3. Institute of Basic Medical Sciences, University of Tsukuba, Ibaraki-305, Niihari-gun, Japan

    Yuji Kimula

Authors
  1. Toshimitsu Watanabe
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  2. Yasukazu Tanaka
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  3. Yuji Kimula
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Watanabe, T., Tanaka, Y. & Kimula, Y. A cytophotometrical study on the centenarian hepatocyte. Virchows Archiv B Cell Pathol 46, 265–268 (1984). https://doi.org/10.1007/BF02890315

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  • DOI: https://doi.org/10.1007/BF02890315

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