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The role of acrocentric chromosomes in Nucleolar Organization

II. Constancy of the nucleolar area independent of the number of acrocentric chromosomes in meningioma cell cultures

Virchows Archiv B volume 13, pages 113–117 (1973)Cite this article

Summary

In our first communication we showed that the nucleoli number is dependent on the number of the acrocentric chromosomes present per cell. In this paper it has been proved that the nucleoli area remains constant independent of the loss or gain of acrocentric chromosomes. From these results it can be concluded that a compensation mechanism, between the nucleolus organizing regions of the acrocentric chromosomes, keeps the production of nucleolar material constant.

Zusammenfassung

In unserer ersten Mitteilung konnte nachgewiesen werden, daß die Nucleolenzahl pro Zelle von der Anzahl der vorhandenen akrozentrischen Chromosomen abhängt. In der vorliegenden Arbeit wird weiter gezeigt, daß die Nucleolenfläche pro Zelle unabhängig von der Anzahl akrozentrischen Chromosomen konstant gehalten wird. Aus diesem Eegebnis wird geschlossen, daß zwischen den nucleolusorganisierenden Regionen der akrozentrischen Chromosomen ein Kompensationsmechanismus besteht, der auch bei Verlust oder Vermehrung von Nucleolusorganisatoren die Produktion von Nucleolusmaterial konstant hält.

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Affiliations

  1. Max-Planck-Institut für Psychiatrie München, Deutschland

    H. Zankl, S. Stengel-Rutkowski & K. D. Zang

Authors
  1. H. Zankl
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  2. S. Stengel-Rutkowski
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  3. K. D. Zang
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Additional information

This study was supported by the Deutsche Forschungsgemeinschaft (Za 32/9).

Dedicated to Prof. Ruhenstroth-Bauer to his 60th birthday.

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Zankl, H., Stengel-Rutkowski, S. & Zang, K.D. The role of acrocentric chromosomes in Nucleolar Organization. Virchows Arch. Abt. B Zellpath. 13, 113–117 (1973). https://doi.org/10.1007/BF02889302

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  • DOI: https://doi.org/10.1007/BF02889302

Keywords

  • Meningioma
  • Acrocentric Chromosome
  • Meningioma Cell
  • Human Meningioma
  • Nucleus Area