Summary
Thein vivo release rate of levonorgestrel-containing silicon capsule (in vitro releasing rate: 6 μg/d) placed in rabbits was determined. The results showed that the average release per year was 8. 32 μg withr being 0. 96000. The release pattern of the levonorgestrel-containing silicon capsule system was proved to be zero-order release. Our study provided some experimental data for clinical use of the system for birth control.
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Chang-jie, W., Xi-rui, W., Wen-jia, X. et al. Study onin vivo release of levonorgestrel-containing silicon capsule. Journal of Tongji Medical University 15, 167–170 (1995). https://doi.org/10.1007/BF02888228
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DOI: https://doi.org/10.1007/BF02888228