Summary
66 patients with dermatophytosis and superficial cutaneous candidiasis have been treated with Ciclopirox Olamine (Batrafen) Cream with a cure rate of 82%. The tinea corporis and cruris responded to Ciclopirox Olamine better than tinea manus and pedis. Itching of most patients disappeared after one week treatment. Eruptions in most patients suffering from tinea corporis and cruris began fading at the end of the first week treatment. Patients with tinea manus and pedis showed clinical improvement in eruption from second to third week after treatment. 11 cases experienced different side effects such as dermatitis, folliculitis and disseminating eczema, but none of them was severe enough to necessitate withdrawal of the treatment. Folloculitis needed anti-inflammatory and antiallergic medication and subsided first to fifth week after discontinuation of the drug. No systemic reaction was noted. 20 % of patients were found to have relapse at second and fourth week follow-up after withdrawal of the drug.
Similar content being viewed by others
Reference
Jue SG, et al. Ciclopirox Olamine 1 % Cream-a preliminary review of its antimicrobial activity and therapeutic use. Drugs 1985; 29(4): 335–40.
Author information
Authors and Affiliations
Rights and permissions
About this article
Cite this article
Yue-chen, Z., Tong-hua, X., Shu-ming, W. et al. Observations on effects of ciclopirox olamine on dermatophytosis. Journal of Tongji Medical University 7, 187–190 (1987). https://doi.org/10.1007/BF02888217
Issue Date:
DOI: https://doi.org/10.1007/BF02888217