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Studies on the antifertility components from Marsdenia koi

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Summary

By random screening test, Marsdenia koi was found to have antifertility activity on SD rat. From MeOH extracts of this plant two steroidal glycosides, marsdekoiside A and B, were isolated, and their structures were elucidated on the basis of spectral evidence and by comparison of the hydrolysis products with the authentic samples. Both are newly identified compounds, and marsdekoiside A has good antifertility activity.

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Authors and Affiliations

  1. Family Planning Research Institute, Tongji Medical University, Wuhan

    Yuan Jin-Ian, Ding Wei-pei & Shi Jian-ping

  2. Shanghai Institute of Materia Medica, Academia Sinica, Shanghai

    Lu Zhi-zhen & Zhou Bing-nan

  3. Program for Collaborative Research in the Pharmaceutical Sciences, College of Pharmacy, University of Illinois at Chicago, 60612, Chicago, Illinois, USA

    Clemens A. J. Erdelmeier, Geoffrey A. Cordell, Harry H. S. Fong & Normann R. Farnsworth

  4. Pharmazeutisches Institut der ETH, CH-8092, Zürich, Switzerland

    Clemens A. J. Erdelmeier

Authors
  1. Yuan Jin-Ian
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  2. Ding Wei-pei
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  3. Shi Jian-ping
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  4. Lu Zhi-zhen
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  5. Zhou Bing-nan
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  6. Clemens A. J. Erdelmeier
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  7. Geoffrey A. Cordell
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  8. Harry H. S. Fong
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  9. Normann R. Farnsworth
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Jin-Ian, Y., Wei-pei, D., Jian-ping, S. et al. Studies on the antifertility components from Marsdenia koi. Journal of Tongji Medical University 11, 165–168 (1991). https://doi.org/10.1007/BF02888129

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  • DOI: https://doi.org/10.1007/BF02888129

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