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The clinic study on synchronous detection of HCV RNA in the plasma and PBMC of hepatitis C patients

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Summary

In order to increase the positive detection rate of HCV RNA in the patients with chronic hepatitis C (CHC), RT-PCR was used to synchronously detect HCV RNA in the plasma and peripheral blood mononuclear cells (PBMC) of 583 CHC patients with a continuously elevated level of ALT for more than one year. The results showed that the positive detection rate of HCV RNA in the plasma of the CHC patients was 19. 2 %, while 24. 5 % in PBMC. It was demonstrated that the positive detection rate for HCV RNA in PBMC was obviously higher than that detected in plasma. To synchronously detect HCV RNA in PBMC by using RT-PCR can increase the positive detection rate of HCV RNA in the CHC patients.

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Authors and Affiliations

  1. Department of Infectious Disease, Xiehe Hospital, Tongji Medical College of Huazhong University of Science and Technology, 430022, Wuhan

    Ye Jin, Liu Wei, Guo Jinsong & Zeng Linglan

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  1. Ye Jin
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  2. Liu Wei
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  3. Guo Jinsong
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  4. Zeng Linglan
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Jin, Y., Wei, L., Jinsong, G. et al. The clinic study on synchronous detection of HCV RNA in the plasma and PBMC of hepatitis C patients. Current Medical Science 21, 110–111 (2001). https://doi.org/10.1007/BF02888070

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  • DOI: https://doi.org/10.1007/BF02888070

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