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Untersuchung der Mastzellen in adenoiden Lebertumoren

Observation of mast cells in adenoid liver tumors

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Zusammenfassung

Mastzellen in Nitrosomorpholin-induzierten adenoiden Lebertumoren der Ratte wurden elektronenmikroskopisch, zytochemisch und morphometrisch untersucht. Alle Befunde sprachen dafür, daß die Mastzellen, die in die epitheliale Komponente der adenoiden Lebertumoren eingestreut sind, Schleimhaut-Mastzellen sind, die, beeinflußt durch einen bisher noch unbekannten Reiz oder Anlockungsfaktor, in die Gangstruktur der Tumoren eingebrochen sind. Die ursprünglich dicht aneinanderliegenden Epithelzellen der Tumoren werden dadurch voneinander getrennt. Unseren Beobachtungen nach dürften die Mastzellen dadurch eine gewisse Rolle bei der Metastasierung der Tumoren spielen.

Abstract

Mast cells in nitrosomorpholine-induced adenoid liver tumors in rats were electronmicroscopically, cytocb, emically and morphometrically examined. All the findings observed sustain the suggestion that the mast cells scattered between the epithelial components of adenoid liver tumors should be mucosa mast cells which wedged into the tubular structures of the tumor as a result of still unknown stimulation or attractive influences of some unidentified factors. The originally closely packed tumor epithelial cells were then divided from each other by the invading mast cells. The present observation revealed that the mast cells may play a certain role in the formation of tumor metastases.

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You-bjng, R., Qing-ping, Z. & Zhong-bi, W. Untersuchung der Mastzellen in adenoiden Lebertumoren. Journal of Tongji Medical University 8, 129–134 (1988). https://doi.org/10.1007/BF02887834

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  • DOI: https://doi.org/10.1007/BF02887834

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