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A modified method for preparation of adriamycin carried by magnetic albumin microspheres

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Summary

The targeting of antineoplastic agents to restricted anatomic sites and specific target cells have been challenged clinicians all the time in cancer chemotherapy, which resulted in recent efforts to focus the effects of existing antitumor agents and treatments on tumor cells and spare their effects on normal cells. The drug-carrier complex, adriamycin carried by magnetic albumin microspheres (ADM-MAM) was prepared by using our discovered new and modified method. The physical feature of the prepared drug-carrier microspheres was much better than by the traditional method in comparison. The successful preparation of the drug-carrier complex, ADM-MAM, is one of the key steps for our later further researches in the targeted chemotherapy.

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Authors and Affiliations

  1. Department of General Surgery, Xiehe Hospital, Tongji Medical College, Huazhong University of Science and Technology, 430022, Wuhan

    Ma Jianhua (Doctor in Charge), Chen Daoda & Tian Yuan

Authors
  1. Ma Jianhua
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  2. Chen Daoda
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  3. Tian Yuan
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Additional information

This project was supported by a grant from the National Health Ministry (No. 67168).

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Jianhua, M., Daoda, C. & Yuan, T. A modified method for preparation of adriamycin carried by magnetic albumin microspheres. Current Medical Science 21, 233–235 (2001). https://doi.org/10.1007/BF02886439

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  • DOI: https://doi.org/10.1007/BF02886439

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