Abstract
Several 4-cyano-1-benzofuranyl-1-butanone derivatives were synthesized and screened for potential antiinflammatory and analgesic activities. The effect of structural variation of these molecules on biological activities was systematically examined. Among these compounds V a , V c and VI e were found to demonstrate a significant antiinflammatory effect. Compounds VI e , V a , I d , I b and VII f were also significantly effective as analgesic ones.
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El-Diwani, H.I., Nakkady, S.S., El-Shabrawy, O. et al. Reactions of some cinnamoyl benzofuran derivatives with activated nitriles and their biological activity. Arch. Pharm. Res. 11, 41–44 (1988). https://doi.org/10.1007/BF02884766
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DOI: https://doi.org/10.1007/BF02884766